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University of Nebraska–Lincoln

Purification Scientist

University of Nebraska–Lincoln, Lincoln, Nebraska, United States, 68511


University of Nebraska-Lincoln Employment Website

Please see Special Instructions for more details.

Click on “Apply for this Job.” You will then either create an application or edit your current application that is on file. You will be required to attach your resume, cover letter, and list of references as three (3) separate documents in MS Word or PDF format.Position Information

Working Title: Purification ScientistDepartment: Bio Process Development Facility-7775Requisition Number: S_240806Posting Open Date: 08/12/2024Application Review Date: 09/06/2024Posting Close Date: Open Until FilledDescription of Work

The Biological Process Development Facility (BPDF) is looking for a purification team member to join our production group. This position will participate in purification process scale-up and optimization to foster the development of therapeutic proteins and other biologics. This position is expected to apply technical and functional knowledge to assist in experiment/project design that will enable the purification team to meet its goals.Job Duties include:

Design and execute purification scale-up and optimization activities related to the production of therapeutic proteins following GLP (Good Laboratory Practice)/GMP (Good Manufacturing Practice).Perform tasks in preparation of and during actual purification runs consisting of equipment preparation, calibration, cleaning, column packing, evaluation and cleaning, solution preparation, processing and system operation.Monitor and troubleshoot development, engineering, and production runs in the development labs and GMP facility.Troubleshoot, design and complete experiments based on data from previous experiments, write scientific reports, and communicate with supervisors.Assist in equipment maintenance.Assist with culture harvest and cGMP fermentation.The BPDF provides biopharmaceutical process development and biomanufacturing services that transition discoveries into early phase clinical trials. This position offers a great opportunity to learn Good Manufacturing Practice (GMP) principles and further develop your technical skills and knowledge of biotherapeutic production. Join our tightly knit collaborative team and play a key role in advancing the development of life-changing biopharmaceuticals.Minimum Required Qualifications

Bachelor’s degree in life sciences/chemical or chemical/biomolecular engineering and two years of experience in a lab environment. Must possess knowledge of the operation principles of purification such as column chromatography, tangential flow filtration, and pump operation. Knowledgeable and experienced in basic laboratory equipment. Knowledge of GLP/GMP requirements for production of biopharmaceuticals. Ability to work well with others in a team environment.Candidates for this position must be a US Citizen, Permanent Resident, Refugee or Asylee in order to work on projects subject to Export Control regulations.Preferred Qualifications

Master’s degree in life sciences/chemical or chemical/biomolecular engineering and five years of experience in a GLP/GMP biopharmaceutical production facility. Experienced performing purification processes such as column chromatography, and TFF. Experience using aseptic technique. Experience operating in a GLP/GMP environment.How to Apply

Click on “Apply for this Job.” You will then either create an application or edit your current application that is on file. You will be required to attach your resume, cover letter, and list of references as three (3) separate documents in MS Word or PDF format.For questions or accommodations related to this position contact Cathy Norquest at cathy.norquest@unl.edu.

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