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University of Washington

RESEARCH SCIENTIST

University of Washington, Seattle, Washington, us, 98127


If you are using a screen reader and experience any difficulty accessing our web pages, please call 206-543-2544 or email UWHires and we will be happy to assist you.Benefits:

As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. The Freedman Lab in the Division of Nephrology, Department of Medicine, is seeking a Research Scientist (Research Scientist/Engineer 3 (E S UAW RSE)) to lead projects using human pluripotent stem cells to develop new treatments for kidney disease, under the general guidance/supervision of Associate Professor Benjamin Freedman.The Research Scientist will combine stem cell culture and differentiation with bioengineering, microfluidics, and pre-clinical animal models to build next-generation models of human kidney regeneration and disease. This position will be responsible for contributing to preparation of reports, papers, presentations, and new proposals. He/she will contribute to positive colleague and investigator relationships through interactions on current grants. The successful applicant will also assist Dr. Freedman with mentoring of trainees. Experience with animals is a plus.This position will be located at South Lake Union campus of UW Medicine, a bastion of stem cell research in the innovative center of Seattle. The successful candidate will be detail-oriented, reliable, highly organized, possess a high degree of accountability for quality of work performed, can work independently and has excellent technical skills.DUTIES AND RESPONSIBILITIESExperimental duties include: 60%Animal work – husbandry, injection, analysis and surgery relevant to kidneysCell culture – daily differentiation and maintenance of human pluripotent stem cellsMicroscopy – immunofluorescence, confocal, wide-field, live cellMicrofluidics – bioengineering, device preparation, input/output bioanalysisGenome editing – guide RNA construction, transfection, screeningDrug discovery – design and execution of high throughput screening assaysBiochemistry and molecular biology – qPCR, electrophoresis, immunoblotting, cloningComputing and analysis – Illustrator, Powerpoint, Excel, Word, ImageJ, HTMLDocumentation – daily record of work performed in files and laboratory notebookLab duties: 20%Mentor research trainees and undergraduates; contribute to improvements in efficiencyOrient/train new staffManage projects of moderate size and scopeAssemble and organize research teamsLead projects or project tasks toward research objectivesInventory management for reagents/orders/cells; track expensesEnsure compliance with lab regulations and completion of corresponding paperworkScholarship: 10%Contribute data and ideas for new projectsDrafting of new grants with minimal supervisionPreparation of primary research manuscripts with minimal supervisionWriting invited manuscriptsAssist in seeking/acquiring additional fundingManage relationships with grants sponsors and progress reportsAnimal care includes: 10%Data collection/maintenance management for rodent colonyUpdating and ensuring compliance with animal welfare protocolsOversight of junior trainees working in the animal facilityDemonstration and training of surgeriesDeveloping new animal protocolsMINIMUM REQUIREMENTSBachelor’s degree in biology, bioengineering, biophysics or related field and at least four years of experience or equivalent combination of education and experience.Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.ADDITIONAL REQUIREMENTSCell culture skills and experience; strong computer skills including Excel, statistical and/or graphical software (ex. Adobe Illustrator, ImageJ, Powerpoint); excellent organizational and communication skills; ability to manage diverse tasks; flexibility in work hours; a thirst for scientific knowledge and progress; comfort working with animal model; and a high degree of integrity.DESIRED QUALIFICATIONSExperience with human pluripotent stem cells, high throughput screening, genome editing (CRISPR/Cas9), or rodent microsurgery.Application Process:

The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”.

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