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Tbwa Chiat/Day Inc

Scientist - Biological Cartography (Royer Group)

Tbwa Chiat/Day Inc, San Francisco, California, United States, 94199


Scientist - Biological Cartography (Royer Group)

The

Chan Zuckerberg Biohub San Francisco

( CZ Biohub SF ) is an independent nonprofit research institute that brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. CZ Biohub SF itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.Our VisionWe pursue large scientific challenges that cannot be pursued in conventional environments.We enable individual investigators to pursue their riskiest and most innovative ideas.The technologies developed at CZ Biohub San Francisco facilitate research by scientists and clinicians at our home institutions and beyond.Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution.The OpportunityDr. Loic A. Royer leads an interdisciplinary team of computer scientists, optical engineers, and biologists with a shared vision: mapping the emergence of cell types and states during embryonic development. This ambitious goal drives the Royer Group to develop cutting-edge technologies. They combine state-of-the-art light-sheet fluorescence microscopy for live, volumetric, and multi-color imaging of zebrafish embryos with advanced image processing and analysis algorithms. This approach enables cell tracking in whole embryos with unprecedented precision and scale. The project's success hinges on seamless collaboration across diverse fields, including transgenic line development, genomics, and more.We are seeking a

Scientist

(PhD-level) who will contribute to building a 'Virtual Zebrafish Embryo' by leveraging these cutting-edge technologies. The successful candidate will be instrumental in advancing our understanding of how embryos develop into fully formed organisms by asking fundamental questions and driving interdisciplinary research. As a key member of our team, you will have the opportunity to work at the frontier of developmental biology, advanced microscopy, single-cell genomics, and computational methods. You will contribute to expanding the Zebrahub platform and play a pivotal role in our mission to create a comprehensive multimodal atlas of cellular behavior in a developing vertebrate organism.You will report directly to Loic A. Royer, Director of Imaging AI and Senior Group Leader of Quantitative Cell Science at CZ Biohub, San Francisco.What You'll DoDesign and execution of experiments using advanced light-sheet microscopy, single-cell genomics, and genetic manipulation.Develop innovative transgenic lines using the latest genome manipulation technologies and protocols to facilitate imaging.Collaborate with computational biologists and computer vision and AI experts on applying novel computational methods to analyze and interpret large-scale imaging and multi-omics datasets.Collaborate closely with genomics, bioengineering, and data science platforms to advance the virtual embryo project.Contribute to enhancing and disseminating your work and the broader Zebrahub resource, making your findings accessible to the global scientific community.Publish high-impact papers and present your work at premier international conferences.What You'll BringPh.D. in Cell Biology, Developmental Biology, Computational Biology, or a related discipline.>5 years of experience in Developmental Biology.>4 years of experience in advanced microscopy techniques.>3 years of experience with transgenic line development, particularly the latest genetic manipulation technologies like CRISPR.>2 years of experience with single-cell genomics protocols and data analysis pipelines.Solid understanding and knowledge of the variety of fluorophores and their use in live imaging.Computational skills, with experience in analyzing large biological datasets.A proven track record of work on interdisciplinary research projects.Excellent written and oral communication skills.A passion for open science and team-oriented research.Nice to haveExperience in light-sheet microscopy.Experience with data integration and analysis.Experience with image processing and analysis.Familiarity with zebrafish as a model system.The Chan Zuckerberg Biohub requires all employees, contractors, and interns, regardless of work location or type of role, to provide proof of full COVID-19 vaccination, including a booster vaccine dose, if eligible, by their start date.CompensationScientist I = $100,000 - $137,500Scientist II = $112,000 - $154,000New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. To determine starting pay, we consider multiple job-related factors including a candidate’s skills, education and experience, market demand, business needs, and internal parity.What We ProvideResources to disrupt and innovate at the frontiers of our knowledge of biology and disease.A collegial and collaborative environment consisting of diverse expertise.Access to collaborators, resources and facilities at our three partner universities (Stanford, UC Berkeley, and UC San Francisco) and at partner organizations in the Bay Area and beyond.Competitive compensation and benefits commensurate with experience.We offer a robust benefits program that enables the important work Biohubbers do every day. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy.The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution.

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