LanceSoft Inc
Research Scientist Research Scientist
LanceSoft Inc, San Diego, California, United States, 92189
Job Title:
Quality - Research ScientistQty:
1Location:
San Diego, CA 92121Duration:
12 MonthsThe starting hourly compensation may be subject to change.Top Skills:Ph.D. in cell biology, immunology, molecular biology, oncology or equivalent fieldKnowledge and experience in using multi-parameter flow cytometryHands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essentialExperience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plusResponsibilities:Utilize and develop multiple disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning.Develop and implement cell-based assays to address both tumor intrinsic cellular biology and immune-based mechanisms of action for potential drug candidates.Design and conduct essential mechanistic experiments in cell biology, cellular biochemistry, molecular biology, and assay development.Accurately maintain written reports and present results in an organized and timely manner.Communicate effectively, foster teamwork, and contribute to collaborative efforts.Strong commitment to quality and demonstrate adaptability.Qualifications:Ph.D. in cell biology, immunology, molecular biology, or equivalent field with 0-2 years of post-doc or industry experience, or M.S. degree with 3+ years of experience, or Bachelor’s degree with 5+ years of experience in the biopharmaceutical industry developing and optimizing cell-based assays, preferably in Oncology.Strong background and experience in cancer research with training in molecular and cell biology.Extensive experience using multi-parameter flow cytometry in the context of primary immune cell isolation and characterization is required.Extensive hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential.Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus.Strong record of high-impact and rigorous science through publication history.Proficiency in scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel/PowerPoint is required.Capability to deliver high quality data in an organized and timely manner.Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.
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Quality - Research ScientistQty:
1Location:
San Diego, CA 92121Duration:
12 MonthsThe starting hourly compensation may be subject to change.Top Skills:Ph.D. in cell biology, immunology, molecular biology, oncology or equivalent fieldKnowledge and experience in using multi-parameter flow cytometryHands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essentialExperience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plusResponsibilities:Utilize and develop multiple disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning.Develop and implement cell-based assays to address both tumor intrinsic cellular biology and immune-based mechanisms of action for potential drug candidates.Design and conduct essential mechanistic experiments in cell biology, cellular biochemistry, molecular biology, and assay development.Accurately maintain written reports and present results in an organized and timely manner.Communicate effectively, foster teamwork, and contribute to collaborative efforts.Strong commitment to quality and demonstrate adaptability.Qualifications:Ph.D. in cell biology, immunology, molecular biology, or equivalent field with 0-2 years of post-doc or industry experience, or M.S. degree with 3+ years of experience, or Bachelor’s degree with 5+ years of experience in the biopharmaceutical industry developing and optimizing cell-based assays, preferably in Oncology.Strong background and experience in cancer research with training in molecular and cell biology.Extensive experience using multi-parameter flow cytometry in the context of primary immune cell isolation and characterization is required.Extensive hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential.Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus.Strong record of high-impact and rigorous science through publication history.Proficiency in scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel/PowerPoint is required.Capability to deliver high quality data in an organized and timely manner.Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.
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