Avid Bioservices
Scientist I, Process Development Viral Vector
Avid Bioservices, Costa Mesa, California, United States, 92626
Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.
Your Role:Join us as a
Scientist I, Process Development Upstream
where you'll harness scientific and engineering concepts to drive viral vector production with mammalian and insect cells. Your role extends beyond the lab bench, encompassing support for cell culture and viral vector technologies, participation in process scale-up, optimization, technology transfer, and validation efforts. You'll be an integral part of both client and internal programs, conducting impactful technical investigations while staying at the forefront of state-of-the-art principles and theories across various scientific disciplines, all while contributing to scientific literature. Make your mark in the world of cutting-edge science and innovation.Cultivate mammalian and insect cell lines for viral vector production using various bioreactor systems and cell culture techniques, ensuring strict aseptic conditions.Conceive and execute well-designed experiments, meticulously analyze results, and derive meaningful insights.Actively engage in supporting both client and internal programs, contributing your expertise to drive successful outcomes.Excel in troubleshooting upstream process issues, proactively brainstorming innovative solutions to overcome upstream challenges.Demonstrate proficiency in operating and troubleshooting essential process equipment, while also pioneering methods and procedures for novel assignments.Maintain comprehensive documentation of data and findings to ensure traceability and regulatory compliance, while regularly updating management on project status and progress.Exhibit strong technical writing skills, creating detailed technical protocols, Process Development reports, guides, SOPs, and other essential documents.Prioritize safety by adhering to all policies, practices, and procedures, promptly reporting any unsafe activities, actively participating in collaborative team efforts to achieve departmental and company goals, and flexibly performing additional duties as assigned.Provide valuable guidance and mentorship to Associate Scientists and Laboratory Assistants, fostering their growth and development.Other tasks as assigned.Minimum Qualifications:Bachelor's degree in Biology, Biochemistry, Immunology, Virology, or an equivalent scientific field, or a combination of education and experience that demonstrates the necessary knowledge and skills.3+ years of relevant and hands-on experience in viral vector, protein, or large molecule production.Hands-on experience with various mammalian and insect cell lines, adherent and suspension cultures, all executed with stringent aseptic technique.Proficiency in working with bioreactors for suspension cultures, showcasing practical expertise in this area.Proficiency in working with multi-layer vessels for adherent cultures, demonstrating hands-on experience.Familiarity with microcarriers is desired and will be considered an asset.Understanding of regulatory requirements and cGMP compliance in bioprocess development.Preferred Qualifications:Proven experience with midsize and large-size single-use bioreactors to produce viral vectors through transfection and/or infection.Physical demands/role specific needs:The work environment for this job occasionally involves exposure to potential electrical shock, toxic or caustic chemicals, vibrations, fumes or airborne particles, wet or humid conditions (non-weather related), and proximity to moving mechanical parts. The noise level in the work environment is occasionally loud. Reasonable accommodations can be made to enable individuals with different abilities to perform the essential functions of the job.Who you are:You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.Your written and verbal skills are out of this world, and you communicate with clarity and confidence.Your proactive approach will be pivotal in maintaining the integrity and quality of our upstream processes.Effective troubleshooting skills are paramount to the success of this role. You must have the ability to identify, analyze, and resolve unexpected challenges in several upstream unit operations.You have exceptional multitasking skills and an unparalleled attention to detail thatensure the smooth running of everything.You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.Work Environment:Regular requirement to sit, talk or hear, use hands to finger, handle or feel, or reach with hands and arms.Frequent requirement to stand and walk.Occasional requirement to climb or balance, stoop, kneel, crouch, or crawl.Regularly lift up to 10 pounds.Occasionally lift up to 20 pounds.Specific vision abilities required include close vision, distance vision, and color vision.Compensation:We offer competitive compensation packages for this role, including a base salary, equity grants, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.The compensation range for this role is $101,300 - $135,000 annually, depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.
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Your Role:Join us as a
Scientist I, Process Development Upstream
where you'll harness scientific and engineering concepts to drive viral vector production with mammalian and insect cells. Your role extends beyond the lab bench, encompassing support for cell culture and viral vector technologies, participation in process scale-up, optimization, technology transfer, and validation efforts. You'll be an integral part of both client and internal programs, conducting impactful technical investigations while staying at the forefront of state-of-the-art principles and theories across various scientific disciplines, all while contributing to scientific literature. Make your mark in the world of cutting-edge science and innovation.Cultivate mammalian and insect cell lines for viral vector production using various bioreactor systems and cell culture techniques, ensuring strict aseptic conditions.Conceive and execute well-designed experiments, meticulously analyze results, and derive meaningful insights.Actively engage in supporting both client and internal programs, contributing your expertise to drive successful outcomes.Excel in troubleshooting upstream process issues, proactively brainstorming innovative solutions to overcome upstream challenges.Demonstrate proficiency in operating and troubleshooting essential process equipment, while also pioneering methods and procedures for novel assignments.Maintain comprehensive documentation of data and findings to ensure traceability and regulatory compliance, while regularly updating management on project status and progress.Exhibit strong technical writing skills, creating detailed technical protocols, Process Development reports, guides, SOPs, and other essential documents.Prioritize safety by adhering to all policies, practices, and procedures, promptly reporting any unsafe activities, actively participating in collaborative team efforts to achieve departmental and company goals, and flexibly performing additional duties as assigned.Provide valuable guidance and mentorship to Associate Scientists and Laboratory Assistants, fostering their growth and development.Other tasks as assigned.Minimum Qualifications:Bachelor's degree in Biology, Biochemistry, Immunology, Virology, or an equivalent scientific field, or a combination of education and experience that demonstrates the necessary knowledge and skills.3+ years of relevant and hands-on experience in viral vector, protein, or large molecule production.Hands-on experience with various mammalian and insect cell lines, adherent and suspension cultures, all executed with stringent aseptic technique.Proficiency in working with bioreactors for suspension cultures, showcasing practical expertise in this area.Proficiency in working with multi-layer vessels for adherent cultures, demonstrating hands-on experience.Familiarity with microcarriers is desired and will be considered an asset.Understanding of regulatory requirements and cGMP compliance in bioprocess development.Preferred Qualifications:Proven experience with midsize and large-size single-use bioreactors to produce viral vectors through transfection and/or infection.Physical demands/role specific needs:The work environment for this job occasionally involves exposure to potential electrical shock, toxic or caustic chemicals, vibrations, fumes or airborne particles, wet or humid conditions (non-weather related), and proximity to moving mechanical parts. The noise level in the work environment is occasionally loud. Reasonable accommodations can be made to enable individuals with different abilities to perform the essential functions of the job.Who you are:You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.Your written and verbal skills are out of this world, and you communicate with clarity and confidence.Your proactive approach will be pivotal in maintaining the integrity and quality of our upstream processes.Effective troubleshooting skills are paramount to the success of this role. You must have the ability to identify, analyze, and resolve unexpected challenges in several upstream unit operations.You have exceptional multitasking skills and an unparalleled attention to detail thatensure the smooth running of everything.You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.Work Environment:Regular requirement to sit, talk or hear, use hands to finger, handle or feel, or reach with hands and arms.Frequent requirement to stand and walk.Occasional requirement to climb or balance, stoop, kneel, crouch, or crawl.Regularly lift up to 10 pounds.Occasionally lift up to 20 pounds.Specific vision abilities required include close vision, distance vision, and color vision.Compensation:We offer competitive compensation packages for this role, including a base salary, equity grants, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.The compensation range for this role is $101,300 - $135,000 annually, depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.
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