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System One

Associate Research Scientist

System One, Seattle, Washington, us, 98127


Job Title : Associate Research Scientist

Location : Seattle, WA

Compensation : $55.00 - 65.50/hr

Type:

Contract, Potential for extension or conversion to permanent

Responsibilities

Execute and troubleshoot process development experiments supporting LNP production and purification.

Assist in the design of experiments and interpretation of data relating to LNP production and purification.

Manage the flow of samples and data and perform analyses.

Optimize workflows for assessing new modes of production and purification.

Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities.

Actively participate and support lab maintenance and continuous improvement initiatives.

Maintain accurate and detailed laboratory notebook and documentation.

Summarize and present data in group meetings and contribute to group discussions and team strategy.

Author technical reports and study memos.

Requirements

Basic Qualifications:

STEM degree with 2+ years of relevant industry experience; title/compensation will ultimately be commensurate with education, experience, and skillset

Demonstrated and extensive experience with TFF and sterile filtration of biological molecules

Experience with JMP for DoE design and analyses

Independently motivated with ability to work in teams

Ability to communicate clearly and concisely through oral presentation and technical writing.

Ability to leverage literature, internal and external resources to solve problems

Desire to identify and advance the cutting edge

Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment

Preferred Qualifications:

Experience with production and purification of LNPs or molecule of similar nature.

Degree in biological or chemical engineering, biochemistry, or bio-related field

Experience with handling of nucleic acids

Experience with LNP characterization techniques (HPLC, DLS, MALs, NTA, etc.)

Experience downstream purification of biological molecules (AKTA, chromatography, TFF, viral filtration, etc.)

Experience with development of continuous processes and implementation process-analytical technologies (PATs)

Experience with microfluidic technologies

Experience in the development of other gene delivery or editing materials (e.g. adeno-, retro-, lenti-, RNPs, Cas, mRNA, etc.)

Benefits

System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

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