GlaxoSmithKline
Scientist Immunology, Cellular and Molecular Analytics US
GlaxoSmithKline, Rockville, Maryland, us, 20849
Scientist Immunology, Cellular and Molecular Analytics US
The role of Scientist Immunology, Cellular and Molecular Analytics US is expected to design and execute scientific studies in support of technical programs as they progress from development into early clinical Phases. The candidate will therefore contribute to the implementation of innovative and cutting-edge analytical methods combining all three technologies and technologies for mRNA and macromolecule (proteins) characterization and testing in line with Quality by Design (QbD) principles in the area of immunology, cellular and molecular biology.Key Responsibilities:Be part and an active member of a High-Performing Team
of top scientists driven by innovation, quality and excellence.Cultivate department culture : excellence in science and operations, embracing an open global mindset, fostering a positive culture of transparency and collaboration within the global organization.Deliver expectations for the following missions :
Develop next generation analytical methods for next generation mRNA vaccines using innovative immuno-based, cell-based and NAT-based technologies and automation in collaboration with the other teams of the global analytical platforms.Apply/execute these methods to early mRNA candidate vaccines in close collaboration with Preclinical, Drug Substance (DS) and Drug Product (DP) teams for deep product understanding, process development support at the preclinical, DS and DP stages.Excel in delivering quality data and sound science to drive decisions for new vaccine candidate projects, as part of end-to-end accelerated vaccine CMC development programs.
Design and drive the development of innovative analytical methods
for vaccine early development phases and integrate it into the end-to-end CMC strategy. Collaborate closely with the Preclinical, Drug Substance and Drug Product departments, as well as with the other ARDS platforms and other stakeholders to ensure timely delivery.Act as a key subject matter expert : think out-of-the-box, using sound science, paying attention to details to continuously improve and shape the CMC strategy & framework.Basic Qualifications:MS or PhD in Molecular Biology, Biotechnology, Bioengineering, Chemical Engineering, or a related scientific field.MS candidates should have three or more years of additional laboratory experience. PhD with no additional laboratory experience is acceptable.Two or more years of experience in immuno-based, cell-based and nucleic acid based technologies.Preferred Qualifications:A good understanding of biopharma / vaccine development process.Has worked in a multi-disciplinary team, demonstrates skills in combining different analytical technologies (immuno-cellular, cellular-molecular, immuno-molecular) in the field.Strong experience and understanding of molecular biology and analytical development.Fluency in English.Good understanding of QbD principles. Driven by excellence, creativity, accountability, and flexibility in a collaborative and innovative environment.Capacity to synthesize messages and ability to defend scientific and technical decisions to have constructive interactions and take the right decisions with other Leaders.Must have the ability to work with cross-functional teams.Superlative presentation skills, across lines and levels and with senior stakeholders.Problem-solving ability with limited information available to make decisions and interpretations.Anticipates medium/long-term future issues.Positive, open and can-do mindset.Critical thinking ability is a must.
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The role of Scientist Immunology, Cellular and Molecular Analytics US is expected to design and execute scientific studies in support of technical programs as they progress from development into early clinical Phases. The candidate will therefore contribute to the implementation of innovative and cutting-edge analytical methods combining all three technologies and technologies for mRNA and macromolecule (proteins) characterization and testing in line with Quality by Design (QbD) principles in the area of immunology, cellular and molecular biology.Key Responsibilities:Be part and an active member of a High-Performing Team
of top scientists driven by innovation, quality and excellence.Cultivate department culture : excellence in science and operations, embracing an open global mindset, fostering a positive culture of transparency and collaboration within the global organization.Deliver expectations for the following missions :
Develop next generation analytical methods for next generation mRNA vaccines using innovative immuno-based, cell-based and NAT-based technologies and automation in collaboration with the other teams of the global analytical platforms.Apply/execute these methods to early mRNA candidate vaccines in close collaboration with Preclinical, Drug Substance (DS) and Drug Product (DP) teams for deep product understanding, process development support at the preclinical, DS and DP stages.Excel in delivering quality data and sound science to drive decisions for new vaccine candidate projects, as part of end-to-end accelerated vaccine CMC development programs.
Design and drive the development of innovative analytical methods
for vaccine early development phases and integrate it into the end-to-end CMC strategy. Collaborate closely with the Preclinical, Drug Substance and Drug Product departments, as well as with the other ARDS platforms and other stakeholders to ensure timely delivery.Act as a key subject matter expert : think out-of-the-box, using sound science, paying attention to details to continuously improve and shape the CMC strategy & framework.Basic Qualifications:MS or PhD in Molecular Biology, Biotechnology, Bioengineering, Chemical Engineering, or a related scientific field.MS candidates should have three or more years of additional laboratory experience. PhD with no additional laboratory experience is acceptable.Two or more years of experience in immuno-based, cell-based and nucleic acid based technologies.Preferred Qualifications:A good understanding of biopharma / vaccine development process.Has worked in a multi-disciplinary team, demonstrates skills in combining different analytical technologies (immuno-cellular, cellular-molecular, immuno-molecular) in the field.Strong experience and understanding of molecular biology and analytical development.Fluency in English.Good understanding of QbD principles. Driven by excellence, creativity, accountability, and flexibility in a collaborative and innovative environment.Capacity to synthesize messages and ability to defend scientific and technical decisions to have constructive interactions and take the right decisions with other Leaders.Must have the ability to work with cross-functional teams.Superlative presentation skills, across lines and levels and with senior stakeholders.Problem-solving ability with limited information available to make decisions and interpretations.Anticipates medium/long-term future issues.Positive, open and can-do mindset.Critical thinking ability is a must.
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