Sarepta Therapeutics
Director, High Throughput Process Automation
Sarepta Therapeutics, Columbus, Ohio, United States, 43224
Director, High Throughput Process Automation
Apply remote type: Onsitelocations: Columbus, OHtime type: Full timeposted on: Posted 22 Days Agojob requisition id: R-02562Why Sarepta? Why Now?The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.What Sarepta OffersAt Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:Physical and Emotional WellnessFinancial WellnessSupport for CaregiversFor a full list of our comprehensive benefits, see our website:
https://www.sarepta.com/join-usThe Importance of the RoleThe Director/ HTPA (High Throughput & Process automation), as a critical team leader of the ERPD (Early Research Process Development) group in GTCOE (Genetic Therapies Center of Excellence) will support Sarepta’s pipeline of cutting-edge recombinant AAV viral vector-based therapies. S/he will continue to build the high throughput and process automation capabilities in the process & analytical development with the team of HTPD scientists and research associates to accelerate the timeline to develop the cutting-edge technology to produce and analyze the high-quality recombinant AAV vectors. S/he will work in a highly interdisciplinary environment and be expected to communicate effectively and productively with the research organization, late-stage PD group, manufacturing group, regulatory, quality, and other cross-functional organizations as needed to achieve rigorous scientific, technical, and product quality expectations.The Opportunity to Make a DifferenceBuild and optimize the existing high throughput platforms and innovative process automation in process & analytical developmentLead the automation scientists and independently implement solutions for high throughput screens using a variety of automation equipmentEvaluate, develop, and implement new technologies to Sarepta's Process & Analytical Development and Manufacturing platformsInitiate investigation of new analytical approaches to a wide range of problems using scientific theory and technical literatureExplore the process characterization with the liquid automatic handler as a qualified scale-down modelWork closely with the team leaders in the ERPD organization and Internal and External research teams to enable platform accelerationActively participate in various early research programs and cross-functional team meetings to play a key role as a subject matter expert for the process and technologyProvide guidance and direction to his/her direct reports; establishes goals, defines roles, supports career development, and manages performanceEnsure accurate and timely analysis of data to support preparation and submission of process and analytical method development reportsSupport regulatory agency questions and prepare the data for regulatory interaction as neededWork seamlessly with cross functional stakeholders to help advance the AAV vector production portfoliosMore about YouAdvanced degree (MS or PhD) in Biochemistry, Bioengineering, Chemical Engineering, or a related field is required with 10+ years of relevant working experience within biotechnology/pharmaceutical industriesExtensive experience and excellent knowledge in high throughput/process automation and programming are requiredHands-on experience with the liquid automatic handler (Tecan or Hamilton) is requiredExperience in managing teams of 5+ scientists/engineers is requiredExperience in process and/or analytical development for viral vectors or other biologics is requiredExperience with gene therapy with recombinant AAV vectors is a plusExcellent written and verbal communication skills are requiredProven record of successfully planning experiments and executing projects in collaboration with internal or external stakeholdersStrong team player who works closely and effectively with cross-functional organizationProven ability to hire & integrate new talent into the organization, manage performance, develop people, and model the company’s core values and cultureWhat Now?We’re always looking for solution-oriented, critical thinkers.So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.This position requires work on site at one of Sarepta’s facilities in the United States.The targeted salary range for this position is $171,200 - $214,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.About Us
Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development. Our vast pipeline is driven by our multi-platform Precision Genetic Medicine Engine in gene therapy, RNA and gene editing.
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Apply remote type: Onsitelocations: Columbus, OHtime type: Full timeposted on: Posted 22 Days Agojob requisition id: R-02562Why Sarepta? Why Now?The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.What Sarepta OffersAt Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:Physical and Emotional WellnessFinancial WellnessSupport for CaregiversFor a full list of our comprehensive benefits, see our website:
https://www.sarepta.com/join-usThe Importance of the RoleThe Director/ HTPA (High Throughput & Process automation), as a critical team leader of the ERPD (Early Research Process Development) group in GTCOE (Genetic Therapies Center of Excellence) will support Sarepta’s pipeline of cutting-edge recombinant AAV viral vector-based therapies. S/he will continue to build the high throughput and process automation capabilities in the process & analytical development with the team of HTPD scientists and research associates to accelerate the timeline to develop the cutting-edge technology to produce and analyze the high-quality recombinant AAV vectors. S/he will work in a highly interdisciplinary environment and be expected to communicate effectively and productively with the research organization, late-stage PD group, manufacturing group, regulatory, quality, and other cross-functional organizations as needed to achieve rigorous scientific, technical, and product quality expectations.The Opportunity to Make a DifferenceBuild and optimize the existing high throughput platforms and innovative process automation in process & analytical developmentLead the automation scientists and independently implement solutions for high throughput screens using a variety of automation equipmentEvaluate, develop, and implement new technologies to Sarepta's Process & Analytical Development and Manufacturing platformsInitiate investigation of new analytical approaches to a wide range of problems using scientific theory and technical literatureExplore the process characterization with the liquid automatic handler as a qualified scale-down modelWork closely with the team leaders in the ERPD organization and Internal and External research teams to enable platform accelerationActively participate in various early research programs and cross-functional team meetings to play a key role as a subject matter expert for the process and technologyProvide guidance and direction to his/her direct reports; establishes goals, defines roles, supports career development, and manages performanceEnsure accurate and timely analysis of data to support preparation and submission of process and analytical method development reportsSupport regulatory agency questions and prepare the data for regulatory interaction as neededWork seamlessly with cross functional stakeholders to help advance the AAV vector production portfoliosMore about YouAdvanced degree (MS or PhD) in Biochemistry, Bioengineering, Chemical Engineering, or a related field is required with 10+ years of relevant working experience within biotechnology/pharmaceutical industriesExtensive experience and excellent knowledge in high throughput/process automation and programming are requiredHands-on experience with the liquid automatic handler (Tecan or Hamilton) is requiredExperience in managing teams of 5+ scientists/engineers is requiredExperience in process and/or analytical development for viral vectors or other biologics is requiredExperience with gene therapy with recombinant AAV vectors is a plusExcellent written and verbal communication skills are requiredProven record of successfully planning experiments and executing projects in collaboration with internal or external stakeholdersStrong team player who works closely and effectively with cross-functional organizationProven ability to hire & integrate new talent into the organization, manage performance, develop people, and model the company’s core values and cultureWhat Now?We’re always looking for solution-oriented, critical thinkers.So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.This position requires work on site at one of Sarepta’s facilities in the United States.The targeted salary range for this position is $171,200 - $214,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.About Us
Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development. Our vast pipeline is driven by our multi-platform Precision Genetic Medicine Engine in gene therapy, RNA and gene editing.
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