CatenaBio
Cell Biologist
CatenaBio - Berkeley, California, United States, 94709
Work at CatenaBio
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$100,000.00/yr - $130,000.00/yr Direct message the job poster from CatenaBio CatenaBio is seeking a motivated and detail-oriented Cell Biologist with hands-on experience in culturing and characterizing cancer cell lines. The ideal candidate will have a strong background in cell-based assays, cancer biology, and in vitro pharmacology. This role will support drug discovery and translational research by executing a variety of cellular and molecular assays to evaluate drug efficacy, mechanism of action, internalization, and bystander effects in cancer models. What You’ll Do Maintain, passage, and characterize human cancer cell lines under aseptic conditions. Design and run in vitro assays: proliferation, cytotoxicity, apoptosis, internalization, and migration/invasion Perform cell viability and metabolic activity assays (e.g., Alamar Blue) Conduct internalization studies for antibody or conjugate-based therapies Utilize flow cytometry for surface marker quantification, apoptosis, and cell cycle analysis Assess bystander effects in co-culture or conditioned media systems. Conduct high-content imaging and immunostaining Accurately document data in electronic lab notebooks and contribute to team discussions and reports Embrace workplace diversity in all its forms Contribute to multidisciplinary teams Thrives in a fast-paced environment and delivers high-quality results Ability to adapt to changing situations while providing ideas and solutions What You Bring M.S. or Ph.D. in Cell Biology, Molecular Biology, Cancer Biology, or related field (B.S. with 5+ years of experience also considered) Proven hands-on experience culturing a variety of cancer cell lines Solid understanding of: Alamar Blue and other viability/metabolic assays Internalization assays Flow cytometry, including surface marker analysis Apoptosis/cell cycle assays (Annexin V, PI, DAPI, EdU/BrdU) Proven track record of problem-solving, data management, and meeting production goals while maintaining high quality standards. Excellent communication skills and ability to collaborate in multidisciplinary teams Experience in the biopharmaceutical industry strongly preferred Strong data analysis, report generation and troubleshooting skills Ability to work independently and thrive in a fast-paced, team-oriented environment Nice to Have Background in immunology, immuno-oncology, or T cell biology is a plus Immunohistochemistry (IHC) and DAPI nuclear staining Experience with T cell activation/proliferation assays (e.g., CFSE, CD69/CD25) Familiarity with 3D tumor spheroids or organoids Background in immuno-oncology or ADC development High-content imaging or automated microscopy Please apply through our job listing below: Seniority level
Seniority level Mid-Senior level Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at CatenaBio by 2x Sign in to set job alerts for “Biologist” roles.
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$100,000.00/yr - $130,000.00/yr Direct message the job poster from CatenaBio CatenaBio is seeking a motivated and detail-oriented Cell Biologist with hands-on experience in culturing and characterizing cancer cell lines. The ideal candidate will have a strong background in cell-based assays, cancer biology, and in vitro pharmacology. This role will support drug discovery and translational research by executing a variety of cellular and molecular assays to evaluate drug efficacy, mechanism of action, internalization, and bystander effects in cancer models. What You’ll Do Maintain, passage, and characterize human cancer cell lines under aseptic conditions. Design and run in vitro assays: proliferation, cytotoxicity, apoptosis, internalization, and migration/invasion Perform cell viability and metabolic activity assays (e.g., Alamar Blue) Conduct internalization studies for antibody or conjugate-based therapies Utilize flow cytometry for surface marker quantification, apoptosis, and cell cycle analysis Assess bystander effects in co-culture or conditioned media systems. Conduct high-content imaging and immunostaining Accurately document data in electronic lab notebooks and contribute to team discussions and reports Embrace workplace diversity in all its forms Contribute to multidisciplinary teams Thrives in a fast-paced environment and delivers high-quality results Ability to adapt to changing situations while providing ideas and solutions What You Bring M.S. or Ph.D. in Cell Biology, Molecular Biology, Cancer Biology, or related field (B.S. with 5+ years of experience also considered) Proven hands-on experience culturing a variety of cancer cell lines Solid understanding of: Alamar Blue and other viability/metabolic assays Internalization assays Flow cytometry, including surface marker analysis Apoptosis/cell cycle assays (Annexin V, PI, DAPI, EdU/BrdU) Proven track record of problem-solving, data management, and meeting production goals while maintaining high quality standards. Excellent communication skills and ability to collaborate in multidisciplinary teams Experience in the biopharmaceutical industry strongly preferred Strong data analysis, report generation and troubleshooting skills Ability to work independently and thrive in a fast-paced, team-oriented environment Nice to Have Background in immunology, immuno-oncology, or T cell biology is a plus Immunohistochemistry (IHC) and DAPI nuclear staining Experience with T cell activation/proliferation assays (e.g., CFSE, CD69/CD25) Familiarity with 3D tumor spheroids or organoids Background in immuno-oncology or ADC development High-content imaging or automated microscopy Please apply through our job listing below: Seniority level
Seniority level Mid-Senior level Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at CatenaBio by 2x Sign in to set job alerts for “Biologist” roles.
Research Associate, Zebrafish Genetic Manipulation (Biohub SF)
Junior or Assistant Specialist- Cho/Cheng Lab
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South San Francisco, CA $50.00-$59.00 6 days ago Research Associate - Experimental Biology (Contract)
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We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr