Senior Scientist/Principal Scientist/Associate Director
ZipRecruiter - Exton, Pennsylvania, United States
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Overview
Senior
Scientist/Principal Scientist/Associate Director
– DMPK Location:
Exton, Pennsylvania Department:
Drug Metabolism and Pharmacokinetics (DMPK) Reports to:
Assistant Vice President Job Summary: We are seeking an experienced and highly motivated Senior Scientist, Principal Scientist, or Associate Director to join our DMPK team. This position offers the opportunity to work in a dynamic environment that supports drug discovery and development programs. Key Responsibilities: Conduct in vitro and in vivo ADME studies using radiolabeled and non-radiolabeled compounds. Perform sample analysis using analytical instruments such as sample oxidizers, liquid scintillation counting (LSC), and LC/MS. Manage laboratory operations, including instrument maintenance, calibration, and documentation of equipment usage and services. Prepare study protocols, oversee study conduct, collect and analyze data, and write/review reports to meet study timelines. Ensure all laboratory operations and record-keeping are compliant with SOPs, DMPK guidelines, study protocols, and applicable regulations. Manage multiple projects simultaneously to meet deadlines, fostering collaboration within the DMPK team. Provide training and mentorship to junior scientists in drug development. Lead cross-functional, matrix-based project teams, guiding them to successful outcomes. Provide scientific leadership and strategic direction to clients and development teams for ongoing and future programs. Qualifications: PhD in Biochemistry, Pharmacology, Chemistry, or related field with 5-10+ years of relevant experience, or Master’s degree with 10-15+ years of experience in DMPK, ADME, or related areas. Extensive experience leading ADME studies, especially with radiolabeled compounds. Proven leadership in managing teams and delivering high-quality data under tight deadlines. Excellent communication and leadership skills, with the ability to collaborate across functions and levels. Knowledge of GLP compliance and EPA regulations is advantageous. Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected status.
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