RTI International
Postdoctoral Chemist-Peptide Research
RTI International, Durham, North Carolina, United States, 27703
Overview
The medicinal chemistry team within the Center for Drug Discovery supports client needs by conducting hit-to-lead and lead optimization. We integrate medicinal chemistry into larger projects focused on drug discovery and development, including computational chemistry, in vitro assay development and HTS screening, in vivo behavioral pharmacology, ADME/PK bioanalytics, and regulatory support.We have an immediate need for a Medicinal Chemist to join an exciting and growing team. Ideally, you will be a highly motivated and organized individual who desires a role
involved in the synthesis of monomers, building blocks, peptides and oligonucleotides
as ligands for various biological targets including kinases, G protein-coupled receptors, ion channels, and antimicrobial targets.At RTI, you will be provided the opportunity to conduct meaningful work in a collaborative, cross-functional environment. We are focused on your career development and provide a generous benefits package that includes tuition reimbursement, parental leave, paid time off, medical/dental, and 401K.This position is a two-year term assignment with potential for annual renewal.
ResponsibilitiesAssist with experimental design.Perform compound synthesis independently or as a member of a team.Ensure proper execution of studies and record-keeping.Perform data analyses and prepare manuscripts for publication.Attend conferences to present novel research findings.Assist with grant applications and laboratory management.Train junior investigators and technicians as needed.Review literature and patents to retrieve scientific information.Other duties as assigned by PI.
QualificationsPh.D. in synthetic or medicinal chemistry or a related discipline field of studyDemonstrated experience across a diverse range of chemical reactions.Highly desirable to possess experience in solid-phase peptide and oligonucleotide synthesis.Proficiency in utilizing RP-HPLC, LC/MS, NMR, and chiral separation techniques.Highly desirable to have experience in cell cultures and/or biological assays.Desirable to possess knowledge of basic computational techniques.Adept at working independently in a fast-paced environment.Proficient in English.RTI is committed to Lead Forward. We innovate, develop talent, collaborate, communicate, think globally, act strategically, and engage inclusively. If that aligns with your values, we would like to hear from you. Join us and experience the RTI Difference.
EEO & Pay Equity StatementsFor San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here.RTI accepts applications to our job openings from candidates with criminal histories or conviction records in accordance with all applicable laws, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States. RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer.At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit-based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance.
Equal Pay Act Minimum/Range$51,000 - $63,000
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The medicinal chemistry team within the Center for Drug Discovery supports client needs by conducting hit-to-lead and lead optimization. We integrate medicinal chemistry into larger projects focused on drug discovery and development, including computational chemistry, in vitro assay development and HTS screening, in vivo behavioral pharmacology, ADME/PK bioanalytics, and regulatory support.We have an immediate need for a Medicinal Chemist to join an exciting and growing team. Ideally, you will be a highly motivated and organized individual who desires a role
involved in the synthesis of monomers, building blocks, peptides and oligonucleotides
as ligands for various biological targets including kinases, G protein-coupled receptors, ion channels, and antimicrobial targets.At RTI, you will be provided the opportunity to conduct meaningful work in a collaborative, cross-functional environment. We are focused on your career development and provide a generous benefits package that includes tuition reimbursement, parental leave, paid time off, medical/dental, and 401K.This position is a two-year term assignment with potential for annual renewal.
ResponsibilitiesAssist with experimental design.Perform compound synthesis independently or as a member of a team.Ensure proper execution of studies and record-keeping.Perform data analyses and prepare manuscripts for publication.Attend conferences to present novel research findings.Assist with grant applications and laboratory management.Train junior investigators and technicians as needed.Review literature and patents to retrieve scientific information.Other duties as assigned by PI.
QualificationsPh.D. in synthetic or medicinal chemistry or a related discipline field of studyDemonstrated experience across a diverse range of chemical reactions.Highly desirable to possess experience in solid-phase peptide and oligonucleotide synthesis.Proficiency in utilizing RP-HPLC, LC/MS, NMR, and chiral separation techniques.Highly desirable to have experience in cell cultures and/or biological assays.Desirable to possess knowledge of basic computational techniques.Adept at working independently in a fast-paced environment.Proficient in English.RTI is committed to Lead Forward. We innovate, develop talent, collaborate, communicate, think globally, act strategically, and engage inclusively. If that aligns with your values, we would like to hear from you. Join us and experience the RTI Difference.
EEO & Pay Equity StatementsFor San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here.RTI accepts applications to our job openings from candidates with criminal histories or conviction records in accordance with all applicable laws, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States. RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer.At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit-based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance.
Equal Pay Act Minimum/Range$51,000 - $63,000
#J-18808-Ljbffr