Flagship Pioneering
Scientist, Protein Analytics
Flagship Pioneering, Cambridge, Massachusetts, us, 02140
What if…
you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?Prologue Medicines is dedicated to transforming drug discovery by leveraging deep biological insights and cutting-edge scientific innovations. Our mission is to deliver breakthrough therapies that address critical unmet medical needs. As part of our dynamic and collaborative team, you will have the opportunity to impact human health on a global scale.Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s 'Change the World' list and has been named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at
www.flagshippioneering.com .Position Overview:Prologue is seeking an experienced and highly motivated scientist with a proven track record of analytical and biophysical characterization of diverse biologic molecules to join our team. The successful candidate will lead the design and execution of analytical evaluation of our protein biologics, helping to drive our platform and therapeutic pipeline forward.They will be responsible for the detailed analytical characterization of early biologics using SDS-PAGE, HPLC/UPLC (SEC, RP, HIC, IEX), light scattering (SEC-MALS, DLS), thermal stability (DSF, DSC) and capillary electrophoresis-based methods (CE-SDS, cIEF). They will also contribute to platform and project advancement through interfacing with matrix teams and managing deliverables related to the Protein Analytics workflows.Key Responsibilities:Contribute to the building of the internal protein analytics capabilities to support project advancement and platform optimizationPerform analytical characterization, being accountable for planning and execution of personal characterization experimentsStay scientifically current and contribute to the implementation of new technologiesAssist in managing external CRO relationships related to protein analyticsAnalyze, document and present on analytical results for novel protein biologicsPrepare and review scientific reports, publications, presentations, and regulatory documents.Maintain a strong sense of teamwork, mentoring colleagues on the development and execution of protein analytical experiments.Qualifications:PhD in Biochemistry or a related discipline with a minimum of 2 years relevant experience in industry required or a MS with 8 years of industry experienceEvidence of creativity in addressing difficult protein analytics challengesExcellent communication, attention to detail, documentation and technical writing skillsAt Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
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you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?Prologue Medicines is dedicated to transforming drug discovery by leveraging deep biological insights and cutting-edge scientific innovations. Our mission is to deliver breakthrough therapies that address critical unmet medical needs. As part of our dynamic and collaborative team, you will have the opportunity to impact human health on a global scale.Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s 'Change the World' list and has been named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at
www.flagshippioneering.com .Position Overview:Prologue is seeking an experienced and highly motivated scientist with a proven track record of analytical and biophysical characterization of diverse biologic molecules to join our team. The successful candidate will lead the design and execution of analytical evaluation of our protein biologics, helping to drive our platform and therapeutic pipeline forward.They will be responsible for the detailed analytical characterization of early biologics using SDS-PAGE, HPLC/UPLC (SEC, RP, HIC, IEX), light scattering (SEC-MALS, DLS), thermal stability (DSF, DSC) and capillary electrophoresis-based methods (CE-SDS, cIEF). They will also contribute to platform and project advancement through interfacing with matrix teams and managing deliverables related to the Protein Analytics workflows.Key Responsibilities:Contribute to the building of the internal protein analytics capabilities to support project advancement and platform optimizationPerform analytical characterization, being accountable for planning and execution of personal characterization experimentsStay scientifically current and contribute to the implementation of new technologiesAssist in managing external CRO relationships related to protein analyticsAnalyze, document and present on analytical results for novel protein biologicsPrepare and review scientific reports, publications, presentations, and regulatory documents.Maintain a strong sense of teamwork, mentoring colleagues on the development and execution of protein analytical experiments.Qualifications:PhD in Biochemistry or a related discipline with a minimum of 2 years relevant experience in industry required or a MS with 8 years of industry experienceEvidence of creativity in addressing difficult protein analytics challengesExcellent communication, attention to detail, documentation and technical writing skillsAt Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
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