Sparxbio
QC scientist
Sparxbio, Mount Prospect, Illinois, United States, 60056
The SparX Group is an emerging biotech powerhouse best known for its multi-specific antibody and antibody drug conjugate (ADC) discovery platforms. With a mission to “Recover Human Immunity by Empowered Antibody Therapies”, SparX has leveraged artificial intelligence to drive its proprietary target mining engine, allowing identification of cellular targets which can best be leveraged for optimal and synergistic biological activity. In addition, SparX has also built in-house GMP facilities of significant capacity in both Chicago and China to produce clinical and commercial drug products, allowing its evolution into an integrated and independent biopharmaceutical company.SparX is seeking an experienced and highly motivated QC specialist (II/III) for QC testing of biologics. The selected candidate will be part of the Quality team to support process development, analytical assay and cGMP activities for antibody drug development and production needs.Required Job Responsibilities:
Perform routine QC analytical assays including but not limited to ELISA, HPLC and SDS-PAGE for therapeutic proteins, antibodies and protein antigens;Conduct sample collection and routine QC testing for WFI system including pH and conductivity measurements;Participate in design, development, optimization and execution of testing methods, analyze and interpret testing results with a minimum of supervision;Follow the SOPs of quality management system (QMS) and participate in practices of OOS handling, investigation and associated CAPA if required;Record, organize and archive all testing documents in compliance with good documentation practice (GDP);Contribute to laboratory organization and maintenance;Adapt to shifting goals and priorities as required.Required Qualifications:
B.S. degree in Biochemistry, Bioengineering, Biology, Chemistry, Pharmaceutical or relevant majors with at least 3 years of analytical experiences in biologics; Advanced degree will be a plus;Basic knowledge and understanding of QC practices in compliance with industry regulations, previous QC experiences in pharmaceutical preferable;Extensive knowledge and experience in analytical testing for QC laboratory including but not limited to HPLC, ELISA and SDS-PAGE;Strong background in protein biochemistry and chromatography with detail-oriented;Knowledge and experience in Quality Management System (QMS) including cGMP manufacturing, GLP and industry compliance will be a great plus;Good documentation and communication skills;Collaborative and proactive working attitude with mindset of teamwork.About SparX Group
SparX Biopharmaceutical Corp. is a research-based development-stage biopharmaceutical company, dedicated to the mission of “strengthening human immunity using robust antibody therapies” through the discovery and development of innovative immuno-oncology agents. Equipped with big data analytical techniques, such as machine learning algorithms, SparX extracts potential interactions from large volumes of complex multi-dimensional public information. Mechanistic pharmacological analyses coupled with in vitro and in vivo evaluations using the syngeneic, transgenic and humanized mouse models, enables SparX’s focus on developing novel or best-in-class therapeutics demonstrating substantial advantages over existing therapies.Target discovery and validation has historically been the bottleneck in drug development. SparX combines its sophisticated target discovery platform with an integrated multi-component SAILING™ antibody optimization system and a cutting-edge bi-ADC technology to markedly improve the success rate of empowered antibody drug development. In addition to the integrated antibody discovery platform, SparX has built in-house cGMP facilities of significant capacity to produce clinical and commercial drug products, facilitating its evolution into an integrated and independent biopharmaceutical company.EEOC Statement:
SparX is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. SparX is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, marital status, sexual orientation, genetic information, uniform service member or veteran status, or any other characteristic protected by federal, state or local law. Further, SparX complies with all applicable national, state, and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. SparX is an e-verify employer.
#J-18808-Ljbffr
Perform routine QC analytical assays including but not limited to ELISA, HPLC and SDS-PAGE for therapeutic proteins, antibodies and protein antigens;Conduct sample collection and routine QC testing for WFI system including pH and conductivity measurements;Participate in design, development, optimization and execution of testing methods, analyze and interpret testing results with a minimum of supervision;Follow the SOPs of quality management system (QMS) and participate in practices of OOS handling, investigation and associated CAPA if required;Record, organize and archive all testing documents in compliance with good documentation practice (GDP);Contribute to laboratory organization and maintenance;Adapt to shifting goals and priorities as required.Required Qualifications:
B.S. degree in Biochemistry, Bioengineering, Biology, Chemistry, Pharmaceutical or relevant majors with at least 3 years of analytical experiences in biologics; Advanced degree will be a plus;Basic knowledge and understanding of QC practices in compliance with industry regulations, previous QC experiences in pharmaceutical preferable;Extensive knowledge and experience in analytical testing for QC laboratory including but not limited to HPLC, ELISA and SDS-PAGE;Strong background in protein biochemistry and chromatography with detail-oriented;Knowledge and experience in Quality Management System (QMS) including cGMP manufacturing, GLP and industry compliance will be a great plus;Good documentation and communication skills;Collaborative and proactive working attitude with mindset of teamwork.About SparX Group
SparX Biopharmaceutical Corp. is a research-based development-stage biopharmaceutical company, dedicated to the mission of “strengthening human immunity using robust antibody therapies” through the discovery and development of innovative immuno-oncology agents. Equipped with big data analytical techniques, such as machine learning algorithms, SparX extracts potential interactions from large volumes of complex multi-dimensional public information. Mechanistic pharmacological analyses coupled with in vitro and in vivo evaluations using the syngeneic, transgenic and humanized mouse models, enables SparX’s focus on developing novel or best-in-class therapeutics demonstrating substantial advantages over existing therapies.Target discovery and validation has historically been the bottleneck in drug development. SparX combines its sophisticated target discovery platform with an integrated multi-component SAILING™ antibody optimization system and a cutting-edge bi-ADC technology to markedly improve the success rate of empowered antibody drug development. In addition to the integrated antibody discovery platform, SparX has built in-house cGMP facilities of significant capacity to produce clinical and commercial drug products, facilitating its evolution into an integrated and independent biopharmaceutical company.EEOC Statement:
SparX is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. SparX is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, marital status, sexual orientation, genetic information, uniform service member or veteran status, or any other characteristic protected by federal, state or local law. Further, SparX complies with all applicable national, state, and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. SparX is an e-verify employer.
#J-18808-Ljbffr