Nanyang Technological University
Wallenberg - NTU Postdoctoral Fellow
Nanyang Technological University, Baltimore, Maryland, United States,
Wallenberg - NTU Postdoctoral Fellow
Apply at NTU Main Campus, Singapore.Full time position posted 30+ Days Ago (Job Requisition ID: R00018252).The Wallenberg-NTU Postdoctoral Fellowship is designed to bring outstanding young researchers, who have graduated from a Swedish university, to NTU for two years of postdoctoral research and studies. The Postdoctoral Fellows are given the opportunity to participate in a broad range of interdisciplinary activities and programs that characterize NTU’s approach to research and education.Key Responsibilities:Conduct molecular dynamics (MD) simulations to investigate the conformational changes and dynamics of specific proteins.Utilize machine learning-driven structure prediction to model and validate potential protein conformations.Analyze free energy landscapes to understand the stability and equilibrium of protein conformations during activation process.Apply structure-based virtual screening (SBVS) using deep learning frameworks to identify and evaluate new small-molecule targeting specific drug targets.Conduct molecular docking and free energy calculations to predict binding affinity and efficacy of potential binders.Collaborate with experimental biologists to validate computational predictions through site-directed mutagenesis and other biochemical assays.Work with medicinal chemists to optimize lead compounds for better affinity, potency, and drug-like properties.Job Requirements:Ph.D. degree related to Computational Biophysics, Molecular Biology, Bioinformatics, or Computational Chemistry.Strong computational skills, including molecular dynamics (MD) simulations, machine learning-driven structure prediction, and enhanced sampling techniques.Skilled in using computational software such as GROMACS and AMBER simulations; proficiency in programming languages like Python for data analysis and machine learning.Good knowledge in computational biophysics, molecular biology, biochemistry, and drug discovery.Demonstrated ability to work collaboratively with structural biologists, medicinal chemists, and experimental biologists.Excellent written and oral communication skills for documenting research findings, preparing reports, and presenting results to diverse audiences.We regret that only shortlisted candidates will be notified.
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Apply at NTU Main Campus, Singapore.Full time position posted 30+ Days Ago (Job Requisition ID: R00018252).The Wallenberg-NTU Postdoctoral Fellowship is designed to bring outstanding young researchers, who have graduated from a Swedish university, to NTU for two years of postdoctoral research and studies. The Postdoctoral Fellows are given the opportunity to participate in a broad range of interdisciplinary activities and programs that characterize NTU’s approach to research and education.Key Responsibilities:Conduct molecular dynamics (MD) simulations to investigate the conformational changes and dynamics of specific proteins.Utilize machine learning-driven structure prediction to model and validate potential protein conformations.Analyze free energy landscapes to understand the stability and equilibrium of protein conformations during activation process.Apply structure-based virtual screening (SBVS) using deep learning frameworks to identify and evaluate new small-molecule targeting specific drug targets.Conduct molecular docking and free energy calculations to predict binding affinity and efficacy of potential binders.Collaborate with experimental biologists to validate computational predictions through site-directed mutagenesis and other biochemical assays.Work with medicinal chemists to optimize lead compounds for better affinity, potency, and drug-like properties.Job Requirements:Ph.D. degree related to Computational Biophysics, Molecular Biology, Bioinformatics, or Computational Chemistry.Strong computational skills, including molecular dynamics (MD) simulations, machine learning-driven structure prediction, and enhanced sampling techniques.Skilled in using computational software such as GROMACS and AMBER simulations; proficiency in programming languages like Python for data analysis and machine learning.Good knowledge in computational biophysics, molecular biology, biochemistry, and drug discovery.Demonstrated ability to work collaboratively with structural biologists, medicinal chemists, and experimental biologists.Excellent written and oral communication skills for documenting research findings, preparing reports, and presenting results to diverse audiences.We regret that only shortlisted candidates will be notified.
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