Moffitt Cancer Center Partnership
Postdoctoral Fellow in Cancer Biology
Moffitt Cancer Center Partnership, Tampa, Florida, us, 33646
Postdoctoral Fellow in Cancer Biology
Location: Tampa, FLFacility: Stabile Research Building (SRB)Department: Molecular OncologySchedule: Full Time - Day Shift - variesAt Moffitt Cancer Center, we strive to be the leader in understanding the complexity of cancer and applying these insights to contribute to the prevention and cure of cancer. Our diverse team of over 9,000 are dedicated to serving our patients and creating a workspace where every individual is recognized and appreciated. For this reason, Moffitt has been recognized on the 2023 Forbes list of America’s Best Large Employers and America’s Best Employers for Women, and has continually been named one of the Tampa Bay Time’s Top Workplace.SummaryPostdoctoral Fellow in Cancer BiologyA postdoctoral position is available in Dr. Lixin Wan’s group at Moffitt Cancer Center Department of Molecular Oncology. The research in Dr. Wan’s lab is focused on protein post-translational modifications. We are interested in understanding how these modifications are misregulated in tumor cells, tumor-infiltrating immune cells, and tumor-interacting stroma cells. We are also interested in developing next-generation techniques to characterize these modifications. Our current projects include the multifaceted roles of ITCH in melanoma and the melanoma immune microenvironment, the context-dependent functions of master cell cycle regulator APC/C in breast cancer and ovarian cancer, the crosstalk between tumor cell aneuploidy and innate immunity, and several others.The lab uses a wide range of approaches in our projects: molecular biology, protein biochemistry,
in vitro
cell culture models, xenograft and syngeneic mouse models, genetically engineered mouse models, various CRISPR-based techniques, and genomic/transcriptomic/proteomic omics techniques.The Ideal Candidate:Experienced in molecular biology, cell biology and biochemistry techniques including cloning, virus delivery system, CRISPR/Cas9 system, DNA/RNA manipulation, protein purification, and immunoblot.Animal handling, mouse modeling and small animal imaging experience.Basic imaging techniques including immunofluorescence, live color imaging.Basic bioinformatics skills.Previous experience in next-generation sequencing techniques (RNA-seq, ChIP-seq, etc) and/or proteomics is a plus.Previous immunology experience is a plus.Responsibilities:Work with PI on project planning; design and conduct experiments independently; document and organize data routinely.Learn and develop research techniques and lab protocols.Develop scientific writing and presentation skills.Work with collaborators and core facility staff on interdisciplinary experiments.Supervise research assistants and graduate students.Credentials and Qualifications:MD or PhD in Cancer Biology, Molecular and Cellular Biology, Genetics or related.Interested applicants should apply online via Moffitt Career site, additionally send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references to Dr. Lixin Wan (Lixin.Wan@moffitt.org).Moffitt Postdocs are provided with Medical (Moffitt covers premium for team member) and eligible for Dental, Vision, Paid Time Off, Retirement, Parental Leave and more. You may be eligible for relocation allowance per policy. Reasons to relocate, aside from the sunshine, beaches and year-round outdoor recreation associated with the Gulf Coast of Florida, Tampa is a thriving metropolitan city, which has become a hub for ground-breaking research, welcoming individuals from around the globe.If you have the vision, passion, and dedication to contribute to our mission,Moffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. We seek candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.Reasonable Accommodation
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job.
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Location: Tampa, FLFacility: Stabile Research Building (SRB)Department: Molecular OncologySchedule: Full Time - Day Shift - variesAt Moffitt Cancer Center, we strive to be the leader in understanding the complexity of cancer and applying these insights to contribute to the prevention and cure of cancer. Our diverse team of over 9,000 are dedicated to serving our patients and creating a workspace where every individual is recognized and appreciated. For this reason, Moffitt has been recognized on the 2023 Forbes list of America’s Best Large Employers and America’s Best Employers for Women, and has continually been named one of the Tampa Bay Time’s Top Workplace.SummaryPostdoctoral Fellow in Cancer BiologyA postdoctoral position is available in Dr. Lixin Wan’s group at Moffitt Cancer Center Department of Molecular Oncology. The research in Dr. Wan’s lab is focused on protein post-translational modifications. We are interested in understanding how these modifications are misregulated in tumor cells, tumor-infiltrating immune cells, and tumor-interacting stroma cells. We are also interested in developing next-generation techniques to characterize these modifications. Our current projects include the multifaceted roles of ITCH in melanoma and the melanoma immune microenvironment, the context-dependent functions of master cell cycle regulator APC/C in breast cancer and ovarian cancer, the crosstalk between tumor cell aneuploidy and innate immunity, and several others.The lab uses a wide range of approaches in our projects: molecular biology, protein biochemistry,
in vitro
cell culture models, xenograft and syngeneic mouse models, genetically engineered mouse models, various CRISPR-based techniques, and genomic/transcriptomic/proteomic omics techniques.The Ideal Candidate:Experienced in molecular biology, cell biology and biochemistry techniques including cloning, virus delivery system, CRISPR/Cas9 system, DNA/RNA manipulation, protein purification, and immunoblot.Animal handling, mouse modeling and small animal imaging experience.Basic imaging techniques including immunofluorescence, live color imaging.Basic bioinformatics skills.Previous experience in next-generation sequencing techniques (RNA-seq, ChIP-seq, etc) and/or proteomics is a plus.Previous immunology experience is a plus.Responsibilities:Work with PI on project planning; design and conduct experiments independently; document and organize data routinely.Learn and develop research techniques and lab protocols.Develop scientific writing and presentation skills.Work with collaborators and core facility staff on interdisciplinary experiments.Supervise research assistants and graduate students.Credentials and Qualifications:MD or PhD in Cancer Biology, Molecular and Cellular Biology, Genetics or related.Interested applicants should apply online via Moffitt Career site, additionally send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references to Dr. Lixin Wan (Lixin.Wan@moffitt.org).Moffitt Postdocs are provided with Medical (Moffitt covers premium for team member) and eligible for Dental, Vision, Paid Time Off, Retirement, Parental Leave and more. You may be eligible for relocation allowance per policy. Reasons to relocate, aside from the sunshine, beaches and year-round outdoor recreation associated with the Gulf Coast of Florida, Tampa is a thriving metropolitan city, which has become a hub for ground-breaking research, welcoming individuals from around the globe.If you have the vision, passion, and dedication to contribute to our mission,Moffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. We seek candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.Reasonable Accommodation
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job.
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