Office of Intramural Training & Education
Principal Scientist - Genomics
Office of Intramural Training & Education, Rockville, Maryland, us, 20849
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
About the position
As a Principal Scientist in the Molecular Analytics team, you will be expected to contribute toward our omics-based program supporting our mRNA-based vaccine discovery efforts. You will join our diverse preclinical research and development team working on cutting-edge technologies in addition to developing new assays suitable for candidate screening and mechanism of action studies.
Qualifications
Basic Qualifications:
Degree in Chemistry, Biology, Biochemistry, Pharmaceutical Sciences, or related scientific field. PhD with 3+ years of post-doc and/or job-related experience, MS with 6+ years of experience, or BS with 9+ years of experience. Six or more years of experience with molecular biology, genomics, transcriptomics, and assay development. Six or more years of experience in molecular biology, including but not limited to: Nucleic acid extraction and quality control, cloning, PCR, qPCR, ddPCR, reverse transcription, RNA in vitro transcription and purification, and various NGS library preparation methods. Two or more years of experience with viral nucleic acid isolation and sequencing. Six or more years of experience in next-generation sequencing technologies (Illumina, Pacific Biosciences, Oxford Nanopore) and their applications, e.g., bulk RNA-seq, single cell omics, immune repertoire profiling.
Preferred Qualifications:
Experience in cell biology and/or virology, including but not limited to: Cell culture, aseptic techniques, cell-based assays, viral tittering, viral genomic isolation, viral neutralization assays, ELISAs. Experience in developing fully custom or customizing commercially available NGS workflows. Proficiency in bioinformatics analysis of data from NGS experiments. Familiarity with automated high-throughput liquid-handling systems. Effective written and oral communication skills as well as presentation skills. Fluency in English. Must be detail oriented; possess problem solving skills, and the ability to handle multiple tasks. Able to efficiently manage uncertainty, changes in priorities and timeline restrictions.
Apply for this vacancy
What you'll need to apply
Submit your application ONLY using the URL provided below. Your application will need your resume to be uploaded. Please do not send to the email listed.
Contact name: Luigi Alvarado
Contact email: Luigi.j.alvarado@gsk.com
Disclaimer/Fine Print
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
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About the position
As a Principal Scientist in the Molecular Analytics team, you will be expected to contribute toward our omics-based program supporting our mRNA-based vaccine discovery efforts. You will join our diverse preclinical research and development team working on cutting-edge technologies in addition to developing new assays suitable for candidate screening and mechanism of action studies.
Qualifications
Basic Qualifications:
Degree in Chemistry, Biology, Biochemistry, Pharmaceutical Sciences, or related scientific field. PhD with 3+ years of post-doc and/or job-related experience, MS with 6+ years of experience, or BS with 9+ years of experience. Six or more years of experience with molecular biology, genomics, transcriptomics, and assay development. Six or more years of experience in molecular biology, including but not limited to: Nucleic acid extraction and quality control, cloning, PCR, qPCR, ddPCR, reverse transcription, RNA in vitro transcription and purification, and various NGS library preparation methods. Two or more years of experience with viral nucleic acid isolation and sequencing. Six or more years of experience in next-generation sequencing technologies (Illumina, Pacific Biosciences, Oxford Nanopore) and their applications, e.g., bulk RNA-seq, single cell omics, immune repertoire profiling.
Preferred Qualifications:
Experience in cell biology and/or virology, including but not limited to: Cell culture, aseptic techniques, cell-based assays, viral tittering, viral genomic isolation, viral neutralization assays, ELISAs. Experience in developing fully custom or customizing commercially available NGS workflows. Proficiency in bioinformatics analysis of data from NGS experiments. Familiarity with automated high-throughput liquid-handling systems. Effective written and oral communication skills as well as presentation skills. Fluency in English. Must be detail oriented; possess problem solving skills, and the ability to handle multiple tasks. Able to efficiently manage uncertainty, changes in priorities and timeline restrictions.
Apply for this vacancy
What you'll need to apply
Submit your application ONLY using the URL provided below. Your application will need your resume to be uploaded. Please do not send to the email listed.
Contact name: Luigi Alvarado
Contact email: Luigi.j.alvarado@gsk.com
Disclaimer/Fine Print
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
#J-18808-Ljbffr