Senior Scientist, Protein Chemistry

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.What You Will AchieveThe Antibody Engineering group is seeking an energetic, highly motivated, and creative Senior Scientist with a strong background in chemical biology, protein chemistry, and/or protein engineering to join Pfizer Oncology’s antibody-drug conjugate (ADC) discovery research team. You will conceive of novel ADC and/or targeted therapy technology platforms and work collaboratively with cancer biologists, immunologists, and translational scientists to advance these ideas into drug candidates. It is expected that the successful candidate will perform hands-on experiments to produce novel ADCs and generate preclinical data, think strategically about how to advance projects, and drive projects to clear go/no-go decision points.How You Will Achieve ItConceptualize novel drug linker, bioconjugate, or protein engineering technology opportunities for therapeutic development (ADC or otherwise)Actively design and execute comprehensive experimental plans comprised of in vitro and in vivo experiments that inform and enable project progressionWork independently and demonstrate the ability to contribute to projects outside their own expertiseEffectively communicate and collaborate across a diverse research department to advance preclinical projectsPresent data at research project team meetings and seminars to drive recommendations for drug discovery and/or development decisionsContribute to and lead programs by executing lead optimization strategies and driving discovery goalsPrepare patent applications and publish impactful researchExpand the capabilities of the Antibody Engineering group by implementing new techniques and cutting-edge technologiesQualificationsMust-HavePh.D. in Chemistry, Biochemistry, Chemical Biology, or related discipline ORM.S. degree in Chemistry, Biochemistry, Chemical Biology, or related discipline with minimum 7 years experience, with 3 of those years in the biopharmaceutical industry ORB.S. degree in Chemistry, Biochemistry, Chemical Biology, or related discipline with minimum 9 years experience, with 5 of those years in the biopharmaceutical industryContemporary knowledge of current chemical, protein engineering, and/or bioconjugation concepts and design tools required for biopharmaceutical drug discoveryExcellent oral and written communication skillsNice-to-HaveTrack record of accomplishment in the biopharmaceutical industry, with examples of high impact publications from scientific work to dateExperience working in matrix teams of scientists to deliver defined objectivesPHYSICAL/MENTAL REQUIREMENTSLift 10 lbsWhy Patients Need YouPfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.The annual base salary for this position ranges from $88,300.00 to $147,100.00.

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