Bruker
Manufacturing Engineer
Bruker, Emeryville, California, United States, 94608
Manufacturing Engineer
Job Locations
US-CA-Emeryville
ID
2024-17062
Job Function
Engineering
Overview
Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker's high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity, and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology.Today, worldwide more than 8500 employees are working on this permanent challenge at over 90 locations on all continents. Bruker continues to build upon its extensive range of products and solutions, its broad base of installed systems and a strong reputation among its customers. Being one of the world's leading analytical instrumentation companies, Bruker is strongly committed to further fully meet its customers' needs as well as to continue to develop state-of-the-art technologies and innovative solutions for today's analytical questions.
As a Manufacturing Engineer, Chips you will drive the sustaining and scale up of the manufacturing process for our proteomics microfluidic consumables product lines. Bruker Cellular Analysis (BCA) consumables are single-use microfluidic chips with proprietary capabilities that enable broad range analysis of single cell or bulk biological cells using microfluidic techniques. Workflows are run using these consumables on our automation instruments for applications in preclinical trials or therapeutic research. You will become the technical lead for all current components, equipment, and assembly processes used to produce the microfluidic consumables as well as their future advancement.
We are looking for a results-oriented engineer to lead this development and sustaining activities for BLI's proteomic consumables. The ideal candidate will have a background in microfluidic chip / cartridge manufacturing, preferably for biological applications, with hands-on experience developing assembly and fabrication processes. The engineer will work closely with multi-disciplinary internal teams and suppliers to scale and deliver product.
Responsibilities
* Manage scale up and sustaining of the proteomics consumables manufacturing process in our CA facility. This includes developing KPIs to track manufacturing performance, proactively addressing process and equipment challenges influencing production, and regularly support production execution to resolve escalations and drive process improvement.* Identify, characterize, and develop solutions to key process inefficiencies. Lead efforts to improve the manufacturability, yield, and reliability of existing consumables. Collaborate with the R&D team and Supply Chain team on cost reduction and capacity expansion efforts as we scale.* Support product sustaining, product development and product improvement by conducting feasibility experiments, working with other internal manufacturing engineers to make prototypes, develop new robust fabrication and assembly processes, verify consumables meet specification requirements, and perform troubleshooting and failure analysis.* Serve as the technical lead for the performance of key nodes and components used in the fabrication of consumables, which include soft polymer (PDMS like materials), injection molded plastics, lyophilized and suspended chemicals and antibodies, and adhesive materials for final packaging. Fabrication processes include polymer mold patterning, polymer bonding (temporary and permanent), liquid and vapor phase chemical deposition, reagent formulation (conjugation, resuspension), Automated and manual reagent dispense, adhesive dispensing and curing, and quality control (QC) metrologies.* From a systematic approach, improve COGS and product stability for the Proteomic Chip Consumable to drive up product margins.* Provide support for validation testing when the data systems teams need an informed user to verify the integrity of our MES, ERP or data warehouse.
Qualifications
Required:* B.S. in Chemical Engineering, Biomedical Engineering, Materials Science, Physics or Engineering.* 2-4 years of experience in a manufacturing setting producing microfluidic devices ideally with biological applications.* Experience in hands-on process development and instrument troubleshooting.* Experience working hands on in a manufacturing environment* Experience working on soft polymer mold patterning, bonding, and chemical processing for microfluidic fabrication.* Data-driven, proficient with design of experiments (DOE), statistical analysis, statistical process control (SPC), failure modes and effects analysis (FMEA), and structured problem solving.* Experience with mechanical 3D design software (e.g. Solidworks) and mechanical fixture, tooling, and equipment design for manufacturing.* Experience with mechanical automation, optical metrology equipment, and acquisition of data off lab instrumentation.* Experience working with injection molded plastics and multilayer, multi material mechanical assemblies.Nice to have:* Experience with failure analysis and analytical materials characterization techniques.* Microfluidic design experience.* Experience working in cleanroom and production manufacturing environment.* An understanding of fluorescent imaging for biological applications.* The ability to write or modify excel formulas, scripts, or other programable logic.Professional Characteristics:* Excellent written and oral communication skills necessary to explain your ideas to cross-functional teams and contract manufacturers with different technical backgrounds* You will have the drive to deliver outstanding products to our customers and the ability to adapt to change (as being on the edge of technology means constantly evolving)* You will need strong personal and team organizational skills to contribute to multi-disciplinary projects* A problem-solving leader with a strong willingness to take ownership and get hands on to characterize and solve problems.* "Get it done" mentality with a willingness to roll up your sleeves and jump into working on the floor to keep equipment, processes, and production on track.At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $91,000 and $147,000 provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions#LI-RD1
Job Locations
US-CA-Emeryville
ID
2024-17062
Job Function
Engineering
Overview
Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker's high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity, and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology.Today, worldwide more than 8500 employees are working on this permanent challenge at over 90 locations on all continents. Bruker continues to build upon its extensive range of products and solutions, its broad base of installed systems and a strong reputation among its customers. Being one of the world's leading analytical instrumentation companies, Bruker is strongly committed to further fully meet its customers' needs as well as to continue to develop state-of-the-art technologies and innovative solutions for today's analytical questions.
As a Manufacturing Engineer, Chips you will drive the sustaining and scale up of the manufacturing process for our proteomics microfluidic consumables product lines. Bruker Cellular Analysis (BCA) consumables are single-use microfluidic chips with proprietary capabilities that enable broad range analysis of single cell or bulk biological cells using microfluidic techniques. Workflows are run using these consumables on our automation instruments for applications in preclinical trials or therapeutic research. You will become the technical lead for all current components, equipment, and assembly processes used to produce the microfluidic consumables as well as their future advancement.
We are looking for a results-oriented engineer to lead this development and sustaining activities for BLI's proteomic consumables. The ideal candidate will have a background in microfluidic chip / cartridge manufacturing, preferably for biological applications, with hands-on experience developing assembly and fabrication processes. The engineer will work closely with multi-disciplinary internal teams and suppliers to scale and deliver product.
Responsibilities
* Manage scale up and sustaining of the proteomics consumables manufacturing process in our CA facility. This includes developing KPIs to track manufacturing performance, proactively addressing process and equipment challenges influencing production, and regularly support production execution to resolve escalations and drive process improvement.* Identify, characterize, and develop solutions to key process inefficiencies. Lead efforts to improve the manufacturability, yield, and reliability of existing consumables. Collaborate with the R&D team and Supply Chain team on cost reduction and capacity expansion efforts as we scale.* Support product sustaining, product development and product improvement by conducting feasibility experiments, working with other internal manufacturing engineers to make prototypes, develop new robust fabrication and assembly processes, verify consumables meet specification requirements, and perform troubleshooting and failure analysis.* Serve as the technical lead for the performance of key nodes and components used in the fabrication of consumables, which include soft polymer (PDMS like materials), injection molded plastics, lyophilized and suspended chemicals and antibodies, and adhesive materials for final packaging. Fabrication processes include polymer mold patterning, polymer bonding (temporary and permanent), liquid and vapor phase chemical deposition, reagent formulation (conjugation, resuspension), Automated and manual reagent dispense, adhesive dispensing and curing, and quality control (QC) metrologies.* From a systematic approach, improve COGS and product stability for the Proteomic Chip Consumable to drive up product margins.* Provide support for validation testing when the data systems teams need an informed user to verify the integrity of our MES, ERP or data warehouse.
Qualifications
Required:* B.S. in Chemical Engineering, Biomedical Engineering, Materials Science, Physics or Engineering.* 2-4 years of experience in a manufacturing setting producing microfluidic devices ideally with biological applications.* Experience in hands-on process development and instrument troubleshooting.* Experience working hands on in a manufacturing environment* Experience working on soft polymer mold patterning, bonding, and chemical processing for microfluidic fabrication.* Data-driven, proficient with design of experiments (DOE), statistical analysis, statistical process control (SPC), failure modes and effects analysis (FMEA), and structured problem solving.* Experience with mechanical 3D design software (e.g. Solidworks) and mechanical fixture, tooling, and equipment design for manufacturing.* Experience with mechanical automation, optical metrology equipment, and acquisition of data off lab instrumentation.* Experience working with injection molded plastics and multilayer, multi material mechanical assemblies.Nice to have:* Experience with failure analysis and analytical materials characterization techniques.* Microfluidic design experience.* Experience working in cleanroom and production manufacturing environment.* An understanding of fluorescent imaging for biological applications.* The ability to write or modify excel formulas, scripts, or other programable logic.Professional Characteristics:* Excellent written and oral communication skills necessary to explain your ideas to cross-functional teams and contract manufacturers with different technical backgrounds* You will have the drive to deliver outstanding products to our customers and the ability to adapt to change (as being on the edge of technology means constantly evolving)* You will need strong personal and team organizational skills to contribute to multi-disciplinary projects* A problem-solving leader with a strong willingness to take ownership and get hands on to characterize and solve problems.* "Get it done" mentality with a willingness to roll up your sleeves and jump into working on the floor to keep equipment, processes, and production on track.At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $91,000 and $147,000 provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions#LI-RD1