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Orbital Therapeutics

Vice President, Translational Biology

Orbital Therapeutics, Cambridge, Massachusetts, us, 02140


Position Summary:

Orbital is seeking a Vice President of Translational Biology with expertise in vaccines and autoimmunity. Reporting to the CSO, the candidate is expected to lead the areas of the company's therapeutic effort. The CSO, the candidate will supervise, motivate, and grow the research teams. They are expected to lead, manage, and analyze technical experiments, including but not limited to immunological, cell biology, and protein assays.

We are looking for candidates who enjoy working in a team, leading scientists and can leverage the growth opportunities that an early-stage startup provides. This is an exceptional opportunity for someone who is excited about cell therapy development and pioneering scientific efforts.

Responsibilities:Work with the leadership team to provide strategy and vision and make decisions that establish objectives for the overall direction of Orbital's research in line with company's portfolio.Innovate novel scientific projects/platforms for the company.Develop essential methods for identifying clinical biomarkers and correlatives, including ensuring the appropriate collection, processing, and analysis of clinical samples.Motivate and grow the research teams to achieve corporate objectives.Oversee the development of preclinical IND packages for portfolio products, including nonclinical study reports and regulatory documents.Work with the Clinical team to develop target candidate profiles and design experiments that support clinical plans.Present experimental findings regularly to the leadership team and supervise the team members as they generate records, and present data.Help draft progress reports and summaries for patent applications and/or scientific publications and provide external representation at conferences.Qualifications:

Ph.D. in immunology, genetics, bioengineering, or a related field.Must have 12 years of postdoctoral experience as well as 7 years within biotechnology/pharmaceutical, including experience performing immunological research.Broad scientific and technical expertise in immunology, particularly in autoimmune diseases and immune-oncology required.Scientific and technical expertise in cell and gene therapy would be a plus.Demonstrated strong ability to lead a team of experienced leaders required.Experience with writing regulatory documents to support FIH studies required.Takes accountability for actions and drives results.Strong interpersonal and presentation skills with good judgment and ability to communicate with a diverse range of individuals.