HireMinds
Sr. Scientist, Protein Biochemistry
HireMinds, Boston, Massachusetts, United States
Sr. Scientist, Protein Biochemistry Location: Boston, Massachusetts HireMinds is representing a clinical-stage biopharmaceutical client that is leading the way in developing biologics. Our clients approach allows them to selectively engage and modulate disease-specific T cells, aiming to transform the treatment landscape for cancer, autoimmune, and inflammatory diseases. Located in an exciting new lab space in Boston's vibrant life sciences corridor they have a collaborative team with hands-on leadership that is present and invested in the team's success. Reach out to HireMinds Biotech team or apply today to learn more You'll Be Responsible For: In this role you'll work as a Scientist or Senior Scientist in a Protein Discovery team and bring your hands-on skill in protein purification and work in protein characterization. Work on mammalian expression of products including engineered Fc-fusion and recombinant proteins Perform protein purification with affinity, ion exchange (IEX), and size-exclusion chromatography (SEC). Progress programs into downstream testing in Quality Control and characterization utilizing methods including SE-HPLC, SDS-PAGE, UV-Vis spectroscopy, and ELISA. Design and execute buffer screens and assays to optimize formulations of protein therapeutics. Ideally you'll bring experience with the optimization of protein conjugation and purification processes. Present your findings through well-structured documentation and engaging oral presentations to peers and management teams. Manage routine maintenance of instrumentation vital to protein biochemistry and collaborate with vendors when necessary. You'll Bring With You: B.S. or M.S. in pharmaceutical, biological, or chemical sciences with 7 years of industry experience, or Ph.D. in a relevant field with 2 years of industrial experience in Biotech or Biopharma. Strong hands-on experience in protein purification and a solid grasp of protein biochemistry. Hands-on experience with instrumentation, including AKTA systems and bioanalytical techniques: HPLC, DSC, SEC-MALS, DSF. Proven ability to design and carry out biochemical or biological assays. Previous experience with protein conjugation chemistry is preferred. This position offers an extraordinary chance for protein biochemists eager to make a significant impact on drug discovery while expanding their professional skills in a collaborative and innovative setting. Become part of our clients mission to redefine treatment options for patients.