Associate Scientist, Analytical Science

Position Summary The Associate Scientist, Analytical Science will manage routine testing, including cell culture, multi-parametric flow cytometry, immunoassay, and cell-based functional assays, to characterize engineered T cell therapy processes and products. Additionally, you will contribute to the daily operational tasks within the Analytical Science team. This role is based in Santa Monica, CA and reports directly to the Director, Product Analytical Science. Responsibilities Perform routine analytical testing for cell culture/passaging, immunophenotyping using multi-parametric flow cytometry, plate-based immunoassays, and luminescent-based cell functional assays (depending on candidate's technological expertise) towards promoting process development and product understanding. Work with Analytical method developers and quality control personnel to improve test methods, draft SOPs and other documents. Be a necessary member of the method monitoring program by documenting test method performance parameters. Support everyday lab operations of analytical laboratories, including critical reagent qualification, equipment management and reagent inventory. Maintain, calibrate and operate analytical equipment and instrumentation that is used routine execution. Complete laboratory tasks or experiments as assigned, and report results by assigned deadlines. Support projects with Process Development and Quality groups. Education and Experience BS degree in Biochemistry, Cell Biology, or related discipline with 1+ years of relevant experience, or Master's degree in Immunology, Molecular Biology, or relevant field. Experience in mammalian cell culture is required. Demonstrate proficiency with implementing plate-based immunoassays (e.g. ELISA, ELLA, Luminex, AlphaLISA), mammalian cell-based potency assays (e.g co-culture, cytotoxicity, proliferation), and multi-color flow cytometry (e.g. BD Fortessa, BD Lyrics, or BD Symphony). Excellent skills with using Microsoft Excel (can maintain complex spreadsheets), Word, and PowerPoint in a scientific environment. Experience using data analysis software (e.g. Prism, JMP, FACSDiva, FlowJo, CytExpert, FCS Express, SoftMax Pro). Experience working in cell therapy area. Experience with Good Documentation Practices and routine testing execution in a regulated environment (e.g. GMP, GLP, or CLIA). Benefits 401(k) plan Paid vacation and holidays; paid leaves Health benefits including medical, prescription drug, dental, and vision coverage.

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