Senior director medical strategy

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Director, Global Medical Strategy, Pancreatic Ductal Adenocarcinoma (PDAC) and Colorectal Cancer (CRC) is a key member of the Medical Affairs team. Reporting to the Executive Director and Head of Medical Strategy for Gastrointestinal Cancers, this individual will be responsible for developing and executing the Global Medical Affairs (GMA) strategy and tactical plans with a focus on launch readiness and life cycle management for medicines across PDAC and CRC indications. The successful candidate will have a proven track record of developing and driving medical strategy for multiple assets with a focus on effectively communicating key scientific data through publications, medical information, medical communications, congress activities as well as gathering insights through Advisory Boards and Key Opinion Leader (KOL) engagements. He/she must work collaboratively with cross-functional counterparts in Development, Research and Commercial as well as other partners in the organization to design and implement a medical strategy for PDAC indications.

Key Responsibilities:

1. Support the development and execution of the multi-year global and US medical strategy for PDAC and CRC, including oversight of the publication and medical communications strategy, integrated evidence planning, lifecycle management and budget planning process.
2. Support the GI Global Medical Affairs Team (GMAT) to execute medical strategies, contribute to the operations and oversight of medical activities associated with PDAC and CRC.
3. Work cross-functionally to support associated pre-launch activities, provide regular updates and support to senior leadership.
4. Lead integrated evidence generation planning in PDAC and CRC including conducting routine cross-functional gap assessments leading to the development/refinement of a publication strategy, an evidence generation plan, and tactical plan as part of the overall GMA plan.
5. Provide medical leadership in scientific engagement activities with key external stakeholders through organizing and leading PDAC and CRC advisory boards, study investigator interactions, congress activities, and peer-to-peer discussions.
6. Serve as a senior medical leader communicating clinical and scientific data to physicians and other healthcare professionals through presentations, educational programs, and scientific discussions.
7. Support medical contribution to cross-functional strategy team meetings including Clinical and Safety sub-teams, product team, Market Access, commercial and other cross-functional strategic discussions.
8. Work closely with the Clinical and MSL teams to provide enrollment, scientific, and engagement support to ensure clinical trials meet study timelines.
9. Partner with RWE strategy and translational teams on related integrated evidence generation strategies and activities as part of the GMA Plan.
10. Partner with Patient Advocacy to incorporate the patient voice and define external medical education strategies for independent grants.
11. Support competitive intelligence team activities through landscape assessments, development of patient journey, and congress insights.
12. Provide medical support for scientific symposia and medical congresses.
13. Support the review and approval of abstracts, manuscripts, corporate communications, and other documents.
14. Provide medical strategy leadership for expanded access programs (EAP) and investigator sponsored research (ISR) for PDAC and CRC.
15. Manage budgets and resources efficiently for GMA supported activities in PDAC and CRC to maximize RevMed resources.
16. Adhere to Revolution Medicines Core Values and policies.

Required Education, Experience, and Skills:

1. An advanced doctorate degree (PharmD, PhD, MD, DO or equivalent) in medical/scientific area is required.
2. Ten years minimum experience in academic medicine, biotech and/or pharmaceutical industry, with at least five years of experience in oncology research and/or patient care.
3. Strong scientific background in oncology with good understanding of biomarker-driven disease.
4. Strong networking skills with deep existing relationships with oncology healthcare professionals including global top key opinion leaders.
5. Experience in KOL mapping and development of engagement plans.
6. Previous overall responsibility and accountability for medical affairs activities, including budget management for more than one compound.
7. Direct, hands-on experience executing the activities of various functions within medical affairs.
8. Extensive experience in global product launches.
9. Proven track record of clinical trial support.
10. Experience conducting gap assessments and executing evidence generation plans.
11. Excellent verbal, written, and presentation skills.
12. Thrives in fast-paced, dynamic environment and can manage multiple priorities.
13. Ability to travel to Redwood City headquarters and professional congresses (30-40%).
14. Manage and adhere to RevMed policies, ensuring compliance with corporate rules and government regulations.

Preferred Skills:

1. Experience in guideline submissions (e.g. NCCN) and engagements with global health authorities preferred.

The base salary range for this full-time position is $240,000 to $294,000 for candidates based at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the minimum and maximum salary for the position in Redwood City and will be adjusted for the local market a candidate is based. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.