SciPro
Research Associate, DMPK
SciPro, Boston, Massachusetts, United States
Are you passionate about scientific discovery and advancing medical innovation? Join a leading pharmaceutical company that’s making breakthroughs in neurology and oncology. Known for its dedication to addressing unmet medical needs, this organization has a strong legacy in research and development, including the creation of a widely-used treatment for Alzheimer’s disease. As part of their ongoing expansion, they are looking for a Principal Researcher/Associate Scientist - DMPK to contribute to their cutting-edge discovery projects. If you thrive in a dynamic, fast-paced environment and want to make a meaningful impact, this opportunity could be your next career move. Role Summary: The Principal Researcher/Associate Scientist will play a critical role on a collaborative, multi-disciplinary team, focusing on LC-MS/MS bioanalytical and in vitro ADME assay technologies. Responsibilities include: Developing bioanalytical methods for quantitative analysis of small molecules using LC-MS/MS. Conducting in vitro ADME studies, including metabolic stability, CYP inhibition, plasma protein binding, and reaction phenotyping. Analyzing pharmacokinetic data and preparing detailed reports. Maintaining workflow logistics, coordinating with internal and external collaborators, tracking study statuses, and managing data in company databases. Ensuring compliance with standard operating procedures and contributing to mechanistic ADME studies or scientific publications when required. Key Qualifications: B.S. in Biology, Chemistry, Pharmaceutical Sciences, or a related field with 5 years of experience, or M.S. with 2 years of experience in industry or a relevant field. Expertise in in vitro ADME studies and analytical techniques (UPLC/HPLC, Triple Quad/TOF Mass Spectrometry). Familiarity with bioanalysis of antibody/ASO using ligand binding assays (LBA, ELISA) is a plus. Proficiency with data analysis software (e.g., Excel, GraphPad, Phoenix). Knowledge of electronic notebooks and mechanistic DMPK is advantageous. Self-motivated and eager to learn new skills. Strong communication skills, both written and oral. Ability to work collaboratively and productively in a team setting.