Integrated Resources Inc.
CAR T-Cell Engineering Scientist
Integrated Resources Inc., South San Francisco, California, us, 94083
Integrated resources is a staffing company.Job Description
The scientist will be involved in establishing methodologies, i.e. culturing and activating primary T-cells, enriching T-cell populations, viral transductions, and electroporation of primary cells, to generate CAR T-cells.They will also be responsible for CAR T-cells based on current state of the art and novel constructs in vitro and in vivo to identify optimal constructs and characteristics for therapeutic uses.Qualifications
BS and 5+ years of experience or MS and 3+ years of experience in an academic and/or industrial setting.Knowledge and hands-on experience in generating and optimizing human CAR T-cells is required.Knowledge and experience of modern laboratory methodology in cellular and molecular T-cell immunology.Knowledge and experience with viral based systems (lenti-virus, adenovirus, or murine retrovirus) to optimize transduction of cell-lines and primary cells.Knowledge and experience in genome engineering (zinc fingers, TALEN, or CRISPR) is preferred.Excellent written and oral communication skills.4-7 years of experience in biochemical techniques.4-7 years of experience in cell/tissue culture techniques.
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The scientist will be involved in establishing methodologies, i.e. culturing and activating primary T-cells, enriching T-cell populations, viral transductions, and electroporation of primary cells, to generate CAR T-cells.They will also be responsible for CAR T-cells based on current state of the art and novel constructs in vitro and in vivo to identify optimal constructs and characteristics for therapeutic uses.Qualifications
BS and 5+ years of experience or MS and 3+ years of experience in an academic and/or industrial setting.Knowledge and hands-on experience in generating and optimizing human CAR T-cells is required.Knowledge and experience of modern laboratory methodology in cellular and molecular T-cell immunology.Knowledge and experience with viral based systems (lenti-virus, adenovirus, or murine retrovirus) to optimize transduction of cell-lines and primary cells.Knowledge and experience in genome engineering (zinc fingers, TALEN, or CRISPR) is preferred.Excellent written and oral communication skills.4-7 years of experience in biochemical techniques.4-7 years of experience in cell/tissue culture techniques.
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