University of California - San Francisco
Biologist - Nuclear Receptors Research
University of California - San Francisco, San Francisco, California, United States, 94199
Biologist - Nuclear Receptors Research
Pharmaceutical ChemistryFull Time79939BRJob Summary
Dr. England's research laboratory (https://pharm.ucsf.edu/england) is developing small molecules to control the activity of nuclear receptors, a class of ligand-regulated transcription factors that play critical roles in human health and disease. The Biologist will characterize the effects of small molecules on the activity of nuclear receptors using cellular assays, including luciferase reporter assays and gene transcription assays (RTqPCR), work up and analyze data (including statistical analyses).Other aspects of the project may involve developing DNA constructs to explore various aspects of nuclear receptor functioning in cells and characterizing ligand effects on the localization and trafficking of nuclear receptors using appropriate microscopic imaging tools and techniques. Must have prior research laboratory experience, be proficient in aseptic techniques, and be willing/able to design and troubleshoot experiments.Required Qualifications
BA/BS in related science including
one year
of recent/directly related work experience utilizing the techniques/methods required by the position; and/or equivalent experience/training.At least one year of experience working with cultured and/or primary cells and carrying out cellular assays in a research laboratory (college laboratory courses are
not
sufficient).Preferred Qualifications
PhD in cellular and molecular biology or related field.Knowledge and/or experience with biophysical methods including microscale thermophoresis (MST), Forster resonance energy transfer (FRET), and fluorescence polarization (FP) assays.About UCSF
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health.Pride Values
UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.Equal Employment Opportunity
The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.
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Pharmaceutical ChemistryFull Time79939BRJob Summary
Dr. England's research laboratory (https://pharm.ucsf.edu/england) is developing small molecules to control the activity of nuclear receptors, a class of ligand-regulated transcription factors that play critical roles in human health and disease. The Biologist will characterize the effects of small molecules on the activity of nuclear receptors using cellular assays, including luciferase reporter assays and gene transcription assays (RTqPCR), work up and analyze data (including statistical analyses).Other aspects of the project may involve developing DNA constructs to explore various aspects of nuclear receptor functioning in cells and characterizing ligand effects on the localization and trafficking of nuclear receptors using appropriate microscopic imaging tools and techniques. Must have prior research laboratory experience, be proficient in aseptic techniques, and be willing/able to design and troubleshoot experiments.Required Qualifications
BA/BS in related science including
one year
of recent/directly related work experience utilizing the techniques/methods required by the position; and/or equivalent experience/training.At least one year of experience working with cultured and/or primary cells and carrying out cellular assays in a research laboratory (college laboratory courses are
not
sufficient).Preferred Qualifications
PhD in cellular and molecular biology or related field.Knowledge and/or experience with biophysical methods including microscale thermophoresis (MST), Forster resonance energy transfer (FRET), and fluorescence polarization (FP) assays.About UCSF
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health.Pride Values
UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.Equal Employment Opportunity
The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.
#J-18808-Ljbffr