Dana-Farber Cancer Institute
Postdoctoral Research Fellow - Chemical and Structural Biology
Dana-Farber Cancer Institute, Boston, Massachusetts, us, 02298
Postdoctoral Research Fellow - Chemical and Structural Biology
Chemical and Structural Biology Postdoctoral Fellowship Position in the Walensky Laboratory, Dana-Farber Cancer Institute.The Walensky laboratory focuses on the chemical biology of deregulated protein interactions in cancer, metabolism, and infectious diseases. Our goal is to dissect and target pathologic protein interactions using multidisciplinary approaches that include (1) chemical and stapled peptide design, (2) rigorous biochemical, proteomic, and structural characterizations, (3) mechanistic validation in cells and mouse models, and ultimately (4) clinical translation. We emphasize mechanistic biology, including (1) canonical and non-canonical roles of BCL-2 family apoptotic proteins, (2) the p53 and RAS pathways, (3) high priority metabolic, bacterial and viral targets, and (4) novel helix-in-groove interactions relevant to protein structure, function, and drug development.We seek a PhD candidate/graduate who is pursuing their first postdoctoral position and has deep experience in structural biology approaches to discern protein interaction mechanisms and blueprints for drug discovery and optimization.ResponsibilitiesWe are currently seeking a highly accomplished PhD candidate/graduate applying for their first postdoctoral fellowship in chemical and structural biology, with a focus on cancer. We are particularly interested in candidates who have solved structures using a spectrum of methods and applied the insights to dissect mechanisms of action.QualificationsPhD in Chemical Biology, Biochemistry, Structural Biology, Biophysics, or a related field is required. Publication track record, including first-authored publications, is preferred.At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. If working in this kind of organization inspires you, we encourage you to apply.Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
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Chemical and Structural Biology Postdoctoral Fellowship Position in the Walensky Laboratory, Dana-Farber Cancer Institute.The Walensky laboratory focuses on the chemical biology of deregulated protein interactions in cancer, metabolism, and infectious diseases. Our goal is to dissect and target pathologic protein interactions using multidisciplinary approaches that include (1) chemical and stapled peptide design, (2) rigorous biochemical, proteomic, and structural characterizations, (3) mechanistic validation in cells and mouse models, and ultimately (4) clinical translation. We emphasize mechanistic biology, including (1) canonical and non-canonical roles of BCL-2 family apoptotic proteins, (2) the p53 and RAS pathways, (3) high priority metabolic, bacterial and viral targets, and (4) novel helix-in-groove interactions relevant to protein structure, function, and drug development.We seek a PhD candidate/graduate who is pursuing their first postdoctoral position and has deep experience in structural biology approaches to discern protein interaction mechanisms and blueprints for drug discovery and optimization.ResponsibilitiesWe are currently seeking a highly accomplished PhD candidate/graduate applying for their first postdoctoral fellowship in chemical and structural biology, with a focus on cancer. We are particularly interested in candidates who have solved structures using a spectrum of methods and applied the insights to dissect mechanisms of action.QualificationsPhD in Chemical Biology, Biochemistry, Structural Biology, Biophysics, or a related field is required. Publication track record, including first-authored publications, is preferred.At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. If working in this kind of organization inspires you, we encourage you to apply.Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
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