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Massachusetts General Physicians’ Organization

IHP Post Doc Research Fellow, Cancer Center

Massachusetts General Physicians’ Organization, Boston, Massachusetts, us, 02298


Job Description - IHP Post Doc Research Fellow, Cancer Center (3302566)POSTDOCTORAL POSITION – Cancer BiologyThe Ellisen laboratory studies fundamental mechanisms of tumorigenesis and their associated therapeutic implications in human cancer. Topics of major interest include breast cancer, novel therapeutic approaches including antibody-drug conjugates, and early cancer pathogenesis. Our work has identified fundamental mechanisms of chromatin reprogramming in tumorigenesis ( Cancer Cell

2017, 31:35), and discovered multiple novel genetic breast cancer drivers ( Nature

2017, 547:55;

Cancer Discovery

2018, 8:336). Our studies of aggressive breast cancers have revealed a genomic signature of homologous recombination deficiency ( Nature Genetics

2017, 49:1476), and we have a deep interest in the genetic pathogenesis ( Science Advances

2020, 6:5), single-cell architecture, and drug resistance of triple-negative breast cancer ( Nature Comms

2017, 9:3588;

Cancer Discovery

2021, 11:2436;

Cancer Cell

2021, 39:1562). Our research is enhanced through a network of expert collaborators in computational biology and high-throughput analysis. Our ability to work at the interface of tumor biology, genetics, and therapeutic application is strongly supported by the basic and clinical research infrastructure of the MGH Cancer Center and Harvard.The position provides a rich intellectual environment, with extensive mentorship and learning opportunities supported by the large research communities of the MGH and Harvard Medical School. The candidate must have recently received a Ph.D. degree in the biological sciences, and must be highly motivated and well versed in basic molecular biology and biochemical techniques. Previous publication in the English-language literature is essential.Primary LocationMA-Charlestown-MGH 13th StreetWork LocationsMGH 13th Street149 13th StreetCharlestown 02129JobMD/PHD/Fellows/PostDocsOrganizationMassachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives, and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.

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