Logo
Dana-Farber Cancer Institute (DFCI)

Postdoctoral Research Fellow - Surgery

Dana-Farber Cancer Institute (DFCI), Boston, Massachusetts, us, 02298


Postdoctoral Research Fellow - SurgeryDana-Farber Cancer InstituteBoston, MAFull Time

The Barbie Laboratory in the department of Breast Oncology at Dana-Farber Cancer Institute/Harvard Medical School focuses on identifying new therapeutic targets for triple negative breast cancer (TNBC).

TNBC is a highly aggressive disease that results in a disproportionate number of metastatic cases and breast cancer deaths. Our laboratory has recently identified a promising pathway that involves STING (Stimulator of interferon genes), which is a critical regulator of the innate immune response to cytoplasmic double stranded DNA (dsDNA) in cancer. Through our research, we seek to gain a more comprehensive understanding of TNBC tumorigenesis and to optimize STING agonist therapy for TNBC.

Responsibilities

Dr. Thanh Barbie is seeking a highly motivated and qualified postdoctoral candidate interested in pursuing several projects aimed at understanding mechanisms of triple negative breast cancer with a focus on its translational applicability to the clinical setting. The projects will have a dual focus on performing

in vitro

mechanistic studies in triple negative breast cancer cell lines and

in vivo

studies using mouse models of triple negative breast cancer.

The position will require a core foundation of molecular and cellular biology, biochemistry, tissue culture, and some basic training in mouse modeling and epigenetics. The successful candidate will be expected to lead and develop multiple independent projects.

Qualifications

The candidate must have a PhD, MD or MD/PhD with several years of relevant experience in molecular biology with some research experience in cancer biology.

For more information and to apply, please visit:

https://careers.dana-farber.org/postdoc-research-fellow-surgery

#J-18808-Ljbffr