[R&D] Senior Research Scientist, CKD

This is a full-time Senior Research Scientist, CKD role that is an on-site position located in Watertown, MA.Primary responsibilities will include, but are not limited to:Conduct research in CKD and provide leadership and innovation by acting as a subject matter expert on kidney diseases.Design and conduct in vivo studies to evaluate efficacy, biomarker identification and analysis, and PK/PD relationship.Design and execute assays for screening of drug candidates (cell-based biochemistry readouts) to identify the mechanism of action of antibodies.Record, analyze, and present scientific data to project teams with clear interpretation of results and propose next steps.Qualifications:Excellent scientific writing and communication skills, as well as strong collaboration and leadership abilities.The ideal candidate must possess scientific details and understanding of the pathophysiology of chronic kidney disease.Ph.D. in cell biology, molecular biology, biochemistry or related life sciences areas with 2-5 years’ industry (Pharma/Biotech) experience or MS in molecular or cell biology with at least 8 years of relevant experience.Experience with angiogenesis will be an advantage.Experience with mouse handling/monitoring, dosing, and tissue/blood collection.Experience working with antibody-based therapeutics.Experience with cell biology and biochemistry techniques, including culture of stable cell lines and primary cells, SDS-PAGE, Western Blot, qPCR, ELISA, chemiluminescence immunoassay (MSD), IHC, IF, reporter assays, transfection, and flow cytometry (including FlowJo).Strong attention to detail and thorough organizational skills.Ability to manage and supervise junior scientists to meet project timelines and teach direct reports assay and troubleshooting skills.Ability to multi-task efficiently, prioritize, and bring projects to conclusion.Ability to work independently in a laboratory setting and collaboratively in a dynamic team setting with strong interpersonal skills.Having willingness and energy to step into new adventures and dare to break new grounds outside of their comfort zone.Experience in drug discovery research is a plus.

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