ADARx Pharmaceuticals Inc.
Scientist
ADARx Pharmaceuticals Inc., San Diego, California, United States, 92189
If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.Scientist
Full Time Scientist, San Diego, CA, US12 days ago Requisition ID: 1018Salary Range: $90,000.00 To 125,000.00 AnnuallyJob DescriptionWe are looking for a highly motivated synthetic organic chemist(s) to join our Discovery Chemistry group to advance cutting-edge RNA drug discovery programs. This individual will be responsible for planning, designing, and executing multi-step synthesis including purification and compound characterization. Active collaboration with colleagues across disciplines, participation in project team meetings, and contribution toward creative problem solving and SAR development are all encouraged.Under general supervision, independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis and prepare related reports.Purify and characterize compounds using a variety of techniques including chromatography, crystallization, trituration, LCMS, NMR, etc.Presentation of results in both written and oral format and delivery of completed reports within a multidisciplinary team.Contribute to the preparation of research reports and presentations for internal project teams, leadership team, and external audience.Establish and maintain excellent working relationships with critical collaborative partners throughout the company.Maintain all appropriate corporate standards for lab safety and hazardous material management; execute daily chemistry operations with an approach designed to minimize risks and hazard waste streams.Maintain updated and well-organized lab notebooks.Manage and maintain equipment, reagents and dedicated laboratory environment needed to carry out assignments.Other duties as assigned.Essential Physical Characteristics:Reasonable accommodation(s) may be made to enable qualified individuals with disabilities to perform the essential functions of a job, on a case-by-case basis.On-Site Protocol:Physical presence at the ADARx Pharmaceuticals worksite is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.Requirements:PhD in Chemistry with 0-2 years of post-doctoral or 0-5 years of pharmaceutical/biotech industry experience in synthetic organic/medicinal chemistry.Familiar with modern chromatographic techniques, automated flash chromatography and modern analytical techniques (NMR, HPLC, LCMS etc).Experience in independently designing synthetic routes and conducting multi-step syntheses.Broad knowledge of scientific experience with track record of scientific achievement demonstrated by peer-reviewed publications.Strong problem-solving skills and a proactive attitude towards exploring new approaches.Must be able to work independently with supervision as needed.Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism.Self-motivated with excellent interpersonal, organizational and communication skills with the ability to take a hands-on approach work effectively in a dynamic and collaborative, fast-paced environment.Good verbal and written communication skills are essential.Superior laboratory skills and awareness of laboratory safety.Proficiency working with Microsoft Word, Excel, Outlook, PowerPoint.Preferred Qualifications:Prior experience in biotech/pharmaceutical industry a plus.A track-record of impacting drug discovery programs through driving projects to key decision points.In-depth knowledge of modern organic synthetic methods, purification and analytical techniques as well as medicinal chemistry.Compensation:This is a full-time position, Monday-Friday, occasional overtime.Pay is commensurate with experience.Equity-based compensationPerformance-based bonuses401(k) with Company MatchFlexible Spending AccountLife InsuranceEmployee Assistance ProgramEmployee DiscountsPaid VacationPaid HolidaysPaid Sick, Jury Duty, BereavementWork Authorization:United States (Required)Company Overview:ADARx Pharmaceuticals, Inc., (the “Company” or “ADARx”) located in San Diego, is a clinical stage biotechnology company committed to turning cutting-edge science into life-saving therapeutics. ADARx has developed proprietary RNA targeting platforms and technology for silencing or editing target mRNA. ADARx has a growing pipeline of RNA targeting therapeutics for treating diseases across a range of therapeutic areas including genetic, cardiometabolic, complement-mediated diseases and central nervous system.ADARx currently has multiple active programs in development with the lead candidate in the clinic. We are well-financed by a syndicate of renowned VC firms.ADARx Pharmaceuticals is an EEO employer committed to an exciting, diverse, and enriching work environment. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
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Full Time Scientist, San Diego, CA, US12 days ago Requisition ID: 1018Salary Range: $90,000.00 To 125,000.00 AnnuallyJob DescriptionWe are looking for a highly motivated synthetic organic chemist(s) to join our Discovery Chemistry group to advance cutting-edge RNA drug discovery programs. This individual will be responsible for planning, designing, and executing multi-step synthesis including purification and compound characterization. Active collaboration with colleagues across disciplines, participation in project team meetings, and contribution toward creative problem solving and SAR development are all encouraged.Under general supervision, independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis and prepare related reports.Purify and characterize compounds using a variety of techniques including chromatography, crystallization, trituration, LCMS, NMR, etc.Presentation of results in both written and oral format and delivery of completed reports within a multidisciplinary team.Contribute to the preparation of research reports and presentations for internal project teams, leadership team, and external audience.Establish and maintain excellent working relationships with critical collaborative partners throughout the company.Maintain all appropriate corporate standards for lab safety and hazardous material management; execute daily chemistry operations with an approach designed to minimize risks and hazard waste streams.Maintain updated and well-organized lab notebooks.Manage and maintain equipment, reagents and dedicated laboratory environment needed to carry out assignments.Other duties as assigned.Essential Physical Characteristics:Reasonable accommodation(s) may be made to enable qualified individuals with disabilities to perform the essential functions of a job, on a case-by-case basis.On-Site Protocol:Physical presence at the ADARx Pharmaceuticals worksite is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.Requirements:PhD in Chemistry with 0-2 years of post-doctoral or 0-5 years of pharmaceutical/biotech industry experience in synthetic organic/medicinal chemistry.Familiar with modern chromatographic techniques, automated flash chromatography and modern analytical techniques (NMR, HPLC, LCMS etc).Experience in independently designing synthetic routes and conducting multi-step syntheses.Broad knowledge of scientific experience with track record of scientific achievement demonstrated by peer-reviewed publications.Strong problem-solving skills and a proactive attitude towards exploring new approaches.Must be able to work independently with supervision as needed.Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism.Self-motivated with excellent interpersonal, organizational and communication skills with the ability to take a hands-on approach work effectively in a dynamic and collaborative, fast-paced environment.Good verbal and written communication skills are essential.Superior laboratory skills and awareness of laboratory safety.Proficiency working with Microsoft Word, Excel, Outlook, PowerPoint.Preferred Qualifications:Prior experience in biotech/pharmaceutical industry a plus.A track-record of impacting drug discovery programs through driving projects to key decision points.In-depth knowledge of modern organic synthetic methods, purification and analytical techniques as well as medicinal chemistry.Compensation:This is a full-time position, Monday-Friday, occasional overtime.Pay is commensurate with experience.Equity-based compensationPerformance-based bonuses401(k) with Company MatchFlexible Spending AccountLife InsuranceEmployee Assistance ProgramEmployee DiscountsPaid VacationPaid HolidaysPaid Sick, Jury Duty, BereavementWork Authorization:United States (Required)Company Overview:ADARx Pharmaceuticals, Inc., (the “Company” or “ADARx”) located in San Diego, is a clinical stage biotechnology company committed to turning cutting-edge science into life-saving therapeutics. ADARx has developed proprietary RNA targeting platforms and technology for silencing or editing target mRNA. ADARx has a growing pipeline of RNA targeting therapeutics for treating diseases across a range of therapeutic areas including genetic, cardiometabolic, complement-mediated diseases and central nervous system.ADARx currently has multiple active programs in development with the lead candidate in the clinic. We are well-financed by a syndicate of renowned VC firms.ADARx Pharmaceuticals is an EEO employer committed to an exciting, diverse, and enriching work environment. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
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