Eli Lilly and Company
Director - Translational Editing
Eli Lilly and Company, Boston, Massachusetts, us, 02298
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.Eli Lilly and Company is seeking a Therapeutic Editing Lead to join our team in Boston, MA.Come join the rapidly expanding Gene Editing team at Eli Lilly! We are responsible for inventing, characterizing, and advancing novel genome editing reagents for a myriad of clinical applications. Our team works cross-functionally within our organization across multiple disease areas and platforms. Our goal is to deliver on the promise of gene editing to patients around the world.Job Responsibilities:Lead efforts cross-functionally with Lilly’s best-in-class expertise in Diabetes, CNS, Immunology, and other areas to develop novel editing programs.Act as the portfolio lead for pre-clinical editing programs, including mentoring individual program leaders. Leadership through Phase1/Phase2 trials may also be needed.Build and develop the team to support the development of gene editing assets.Direct efforts within the Off-Target team to quantify risk profiles in therapeutically relevant cell models.Participate, lead, or evaluate external research programs to bolster the genetic medicine portfolio at Lilly.Support the broader program in design and execution of key in vivo studies both internally and through CROs.Basic Qualifications:PhD in scientific field with 5+ years related work experience.Additional Skills/Preferences:
Mastery of CRISPR-based editing in translational models, including primary cells, pre-clinical disease models, and large animal IND-enabling models.Direct experience leading regulatory submissions for gene editing products.Deep scientific knowledge of lipid nanoparticles and AAV packaging of gene editing components.Significant experience in either liver biology or neurodegeneration.Strong background in molecular biology assays, including qPCR, dPCR, HPLC, MS, and related technologies needed for advanced characterization of editing.Additional Information:This role may require up to 10-15% travel for conferences or training and will include the opportunity to mentor and train junior scientists. The position is located at 15 Necco St, Boston, MA 02210. Full time (40 hours/week). To apply, submit resume via this site.
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Mastery of CRISPR-based editing in translational models, including primary cells, pre-clinical disease models, and large animal IND-enabling models.Direct experience leading regulatory submissions for gene editing products.Deep scientific knowledge of lipid nanoparticles and AAV packaging of gene editing components.Significant experience in either liver biology or neurodegeneration.Strong background in molecular biology assays, including qPCR, dPCR, HPLC, MS, and related technologies needed for advanced characterization of editing.Additional Information:This role may require up to 10-15% travel for conferences or training and will include the opportunity to mentor and train junior scientists. The position is located at 15 Necco St, Boston, MA 02210. Full time (40 hours/week). To apply, submit resume via this site.
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