Intellia Therapeutics
Vice President, General Manager – TTR
Intellia Therapeutics, Cambridge, Massachusetts, us, 02140
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How you will Achieve More at Intellia:
This position will be responsible for building, leading and managing the global development and commercialization of the program in order to maximize its future clinical and commercial success.
The GM will also serve as the Program Leader and will be responsible for working collaboratively with all functional areas to optimize the overall product opportunity, including time to BLA approval and launch and future commercial uptake thereafter.
Summary of Key Responsibilities:
Serve as the ultimate point of accountability to lead the global development and commercialization of NTLA-2001 TTR-Amyloidosis Program
Establish and drive program vision and strategy, ensuring alignment with corporate objectives across the entire portfolio, including longer-term vision for the company
Oversee and lead a team of cross-functional experts across R&D, CMC, Medical Affairs, Access, Commercial, and G&A
Responsible for P&L management, ensuring program investment is in line with maximizing commercial success
In partnership with Program Management, ensure that appropriate prioritization, adequate resource allocation (money and people), timeline planning and quality checkpoints are met to optimize the program (timeline and deliverables)
Integrate information across all aspects of the program to identify, weigh, and balance opportunities and risks, ensuring successful execution of program strategy to both near-term achievement and successful long-term outcomes
In partnership with PM, drive alignment of program strategy and execution with Executive Leadership, and Function Heads for key program/corporate decisions
Engage all levels of management to escalate and resolve conflicts, remove obstacles, and support the development of program team members
The GM will also:
Be part of the leadership team at Intellia and report directly to the CEO, with additional accountability to the Executive Leadership Team
Serve as a key member of the Development Leadership Team under the CMO to ensure the bridge from Development to Commercial is successful for the program
Examples of cross-functional work the GM will lead (not an exhaustive list):
Work with Clinical and Med Affairs to launch awareness and patient identification programs globally to boost referral and clinical enrollment
Team-up with Regulatory, Clinical Development, Medical Affairs, Access, Commercial and others to develop early-on a unique and competitive BLA filing and registration plan for other countries in line with commercial launch strategy
Work with Med Affairs and Commercial to develop intensive patient identification programs and build a centralized information system of commercial leads
Partner with Med Affairs, Access, and Commercial to develop an innovative, comprehensive, and competitive Access strategy supported by adequate evidence generation and through external engagements to overcome obstacles, paving a path for efficient delivery of product to patients while ensuring successful reimbursement
Develop with Program Management and FP&A, a 5-year strategic and 1-year tactical plan in order to optimize resources (money and people)
Manage any strategic alliances related to the program
Work closely with Commercial and others to develop market assessment, lay out and plan all pre-launch activities with a focus on defining and targeting the fastest path to a successful launch upon official regulatory approval of marketing application
Work closely with Commercial and others to develop a competitive marketing campaign and execute on the global go-to-market strategy
About you:
Cross-functional program leadership experience with a strong record of accomplishment in biotech or pharma
Scientific/advanced degree preferred
15+ years progressive Biopharmaceuticals experience, with a background in rare disease development. Direct experience in gene therapy and/or gene-editing a plus
Deep knowledge of external landscape, drug development, and path to commercialization
Commercial launch experience, including international responsibilities preferred
Enterprise mindset with ability to develop and adapt strategy in a complex and evolving landscape
Financial acumen with an established track record of budget oversight, accountability, and managing program investment decisions
Team leadership, executive presence, and the ability to make things happen
Proactive “hands on” individual with collaborative orientation who manages teams effectively, is very self-motivated and can smoothly establish strong working relationships within both internal and external organizations
Decisive and collaborative, with ability to guide teams through managing complex scenarios leading to strong recommendations on path forward
Excellent interpersonal skills with particular emphasis on communication, influencing, and relationship building (at all levels)
Motivated to be part of an organization that aims to make a huge difference through successful launch of new medicines.
#J-18808-Ljbffr
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How you will Achieve More at Intellia:
This position will be responsible for building, leading and managing the global development and commercialization of the program in order to maximize its future clinical and commercial success.
The GM will also serve as the Program Leader and will be responsible for working collaboratively with all functional areas to optimize the overall product opportunity, including time to BLA approval and launch and future commercial uptake thereafter.
Summary of Key Responsibilities:
Serve as the ultimate point of accountability to lead the global development and commercialization of NTLA-2001 TTR-Amyloidosis Program
Establish and drive program vision and strategy, ensuring alignment with corporate objectives across the entire portfolio, including longer-term vision for the company
Oversee and lead a team of cross-functional experts across R&D, CMC, Medical Affairs, Access, Commercial, and G&A
Responsible for P&L management, ensuring program investment is in line with maximizing commercial success
In partnership with Program Management, ensure that appropriate prioritization, adequate resource allocation (money and people), timeline planning and quality checkpoints are met to optimize the program (timeline and deliverables)
Integrate information across all aspects of the program to identify, weigh, and balance opportunities and risks, ensuring successful execution of program strategy to both near-term achievement and successful long-term outcomes
In partnership with PM, drive alignment of program strategy and execution with Executive Leadership, and Function Heads for key program/corporate decisions
Engage all levels of management to escalate and resolve conflicts, remove obstacles, and support the development of program team members
The GM will also:
Be part of the leadership team at Intellia and report directly to the CEO, with additional accountability to the Executive Leadership Team
Serve as a key member of the Development Leadership Team under the CMO to ensure the bridge from Development to Commercial is successful for the program
Examples of cross-functional work the GM will lead (not an exhaustive list):
Work with Clinical and Med Affairs to launch awareness and patient identification programs globally to boost referral and clinical enrollment
Team-up with Regulatory, Clinical Development, Medical Affairs, Access, Commercial and others to develop early-on a unique and competitive BLA filing and registration plan for other countries in line with commercial launch strategy
Work with Med Affairs and Commercial to develop intensive patient identification programs and build a centralized information system of commercial leads
Partner with Med Affairs, Access, and Commercial to develop an innovative, comprehensive, and competitive Access strategy supported by adequate evidence generation and through external engagements to overcome obstacles, paving a path for efficient delivery of product to patients while ensuring successful reimbursement
Develop with Program Management and FP&A, a 5-year strategic and 1-year tactical plan in order to optimize resources (money and people)
Manage any strategic alliances related to the program
Work closely with Commercial and others to develop market assessment, lay out and plan all pre-launch activities with a focus on defining and targeting the fastest path to a successful launch upon official regulatory approval of marketing application
Work closely with Commercial and others to develop a competitive marketing campaign and execute on the global go-to-market strategy
About you:
Cross-functional program leadership experience with a strong record of accomplishment in biotech or pharma
Scientific/advanced degree preferred
15+ years progressive Biopharmaceuticals experience, with a background in rare disease development. Direct experience in gene therapy and/or gene-editing a plus
Deep knowledge of external landscape, drug development, and path to commercialization
Commercial launch experience, including international responsibilities preferred
Enterprise mindset with ability to develop and adapt strategy in a complex and evolving landscape
Financial acumen with an established track record of budget oversight, accountability, and managing program investment decisions
Team leadership, executive presence, and the ability to make things happen
Proactive “hands on” individual with collaborative orientation who manages teams effectively, is very self-motivated and can smoothly establish strong working relationships within both internal and external organizations
Decisive and collaborative, with ability to guide teams through managing complex scenarios leading to strong recommendations on path forward
Excellent interpersonal skills with particular emphasis on communication, influencing, and relationship building (at all levels)
Motivated to be part of an organization that aims to make a huge difference through successful launch of new medicines.
#J-18808-Ljbffr