Ensoma
Principal Scientist/Associate Director, Protein Engineering
Ensoma, Boston, Massachusetts, us, 02298
We seek an energetic and motivated Principal Scientist or Associate Director to lead the design and execution of strategies to engineer hematopoietic stem cells by a combination of genetic and protein engineering approaches.
You will join a team of scientists dedicated to moving a novel gene therapy drug candidate into the clinic. Join us and be part of building a company revolutionizing the reach and access of the curative power of genomic medicines for patients with serious diseases.
Responsibilities:
Lead the design and testing of fusion proteins and antibodies in different formats to optimize their function.
Lead therapeutic antibody selection, design and optimization for antibody discovery programs.
Oversee the development of assays to screen and test the function and affinity of antibodies and recombinant proteins.
Manage CROs in development and characterization of therapeutic antibodies, developing and guiding the research plan and ensuring timely delivery of data.
Qualifications:Required:
A Doctoral Degree in biochemistry, molecular biology or related field with a minimum of eight years of experience in the biotechnology/pharmaceutical industry and/or an academic setting (industry experience is preferred).
Demonstrated expertise applying molecular biology and protein engineering approaches to optimize the function of antibodies and other proteins.
Proficiency in molecular biology techniques.
Experience expressing proteins in mammalian cells.
Experience developing and implementing functional and affinity assays to characterize antibodies.
Hands-on experience using display approaches to select and screen novel therapeutic antibodies.
About Ensoma:Ensoma is a place where you can ask the big questions. We look at gene therapy today and ask: What if we could eliminate the patient burden? What if we could treat diseases that affect millions? What if we could treat people anywhere around the world?
Ensoma was founded to answer these questions through our Engenious platform that can transform the hematopoietic (blood & immune) system with a single treatment. Our Engenious gene therapy platform is the first to precisely engineer any or all hematopoietic and immune cells with a one-time, off-the-shelf
in vivo
treatment. Engenious therapies have an unmatched capacity to deliver all modern genetic modification tools and set a new standard for versatile cell programming and control across a range of complex diseases. We believe the future of medicine lies within us – and this bigger, bolder vision for gene therapy needs incredible people to make it a reality.
For our team, realizing this vision is personal. Founded and guided by leaders drawn from the top of the cell and gene therapy field, we feel an urgency and passion for our work driven by its potential global impact.
A meeting at Ensoma is a space where curiosity, trust, authenticity, problem-solving and professional development are celebrated. A career at Ensoma is an opportunity to be part of the team building the future of medicine.
Ensoma is supported by top-tier investors, a strategic collaboration with Takeda and a passionate team committed to a bold global vision for gene therapy. Ensoma is based in Boston, Massachusetts. For more information, please visit
www.ensoma.com .
#J-18808-Ljbffr
You will join a team of scientists dedicated to moving a novel gene therapy drug candidate into the clinic. Join us and be part of building a company revolutionizing the reach and access of the curative power of genomic medicines for patients with serious diseases.
Responsibilities:
Lead the design and testing of fusion proteins and antibodies in different formats to optimize their function.
Lead therapeutic antibody selection, design and optimization for antibody discovery programs.
Oversee the development of assays to screen and test the function and affinity of antibodies and recombinant proteins.
Manage CROs in development and characterization of therapeutic antibodies, developing and guiding the research plan and ensuring timely delivery of data.
Qualifications:Required:
A Doctoral Degree in biochemistry, molecular biology or related field with a minimum of eight years of experience in the biotechnology/pharmaceutical industry and/or an academic setting (industry experience is preferred).
Demonstrated expertise applying molecular biology and protein engineering approaches to optimize the function of antibodies and other proteins.
Proficiency in molecular biology techniques.
Experience expressing proteins in mammalian cells.
Experience developing and implementing functional and affinity assays to characterize antibodies.
Hands-on experience using display approaches to select and screen novel therapeutic antibodies.
About Ensoma:Ensoma is a place where you can ask the big questions. We look at gene therapy today and ask: What if we could eliminate the patient burden? What if we could treat diseases that affect millions? What if we could treat people anywhere around the world?
Ensoma was founded to answer these questions through our Engenious platform that can transform the hematopoietic (blood & immune) system with a single treatment. Our Engenious gene therapy platform is the first to precisely engineer any or all hematopoietic and immune cells with a one-time, off-the-shelf
in vivo
treatment. Engenious therapies have an unmatched capacity to deliver all modern genetic modification tools and set a new standard for versatile cell programming and control across a range of complex diseases. We believe the future of medicine lies within us – and this bigger, bolder vision for gene therapy needs incredible people to make it a reality.
For our team, realizing this vision is personal. Founded and guided by leaders drawn from the top of the cell and gene therapy field, we feel an urgency and passion for our work driven by its potential global impact.
A meeting at Ensoma is a space where curiosity, trust, authenticity, problem-solving and professional development are celebrated. A career at Ensoma is an opportunity to be part of the team building the future of medicine.
Ensoma is supported by top-tier investors, a strategic collaboration with Takeda and a passionate team committed to a bold global vision for gene therapy. Ensoma is based in Boston, Massachusetts. For more information, please visit
www.ensoma.com .
#J-18808-Ljbffr