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Pfizer, S.A. de C.V

Senior Principal Scientist - Immune Cell Engager

Pfizer, S.A. de C.V, California, Missouri, United States, 65018


Senior Principal Scientist - Immune Cell Engager

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most.What You Will Achieve

Pfizer’s Oncology Research Unit (ORU) in La Jolla, California, is seeking a Senior Principal Scientist (PhD) to join the Tumor Immunity team focused on delivering breakthroughs that change patients’ lives by redirecting the immune system against cancer. The Senior Principal Scientist will be responsible for driving scientific strategies and their implementation within a collaborative team of motivated and rigorous scientists to advance immuno-oncology programs within our pre-clinical portfolio.Our ideal candidate will have:A deep expertise in biology, immunology and the development of therapeutic immune (T and/or NK) cell engagersStrong leadership as demonstrated by a track record of building and managing high performing teams of PhD and non-PhD level scientistsExperience in effectively leading cross-functional teams within a matrixed environmentThe successful candidate will demonstrate a proven track record of scientific leadership and productivity as evidenced by impact on drug discovery programs and research publications in scientific journals.How You Will Achieve It

Lead research project teams to develop and execute on research strategy and development objectives aligned with ORU strategic focus areasProvide scientific leadership to preclinical project teams serving as the biology lead to design, plan, and execute laboratory experiments and deliver high-quality decision-making data sets in support of project objectives and timelinesFoster and maintain strong collaborative relationships across the ORU discovery organization to design experiments and interpret data sets, driving pipeline advancementsStrengthen department’s overall immuno-oncology capabilities and expertise by employing innovative methods and technologies to test therapeutic hypothesesPresent research findings and share learnings at research project team meetings and research forums and support the development of team members in these settingsManage and mentor scientists in both laboratory based and discipline leadership roles to support preclinical discovery research programs within a matrixed environmentActively contribute to preparation of required drug development and regulatory documents (e.g., IND submissions), with responsibilities for non-clinical pharmacology data packagesEffectively communicate program strategy, methodology, progress, and challenges to multiple stakeholders and partners, including senior executives and governance committeesQualifications

PhD in immunology, cancer biology or relevant biological science with 8+ years of relevant postdoctoral experience.Must have industry experience leading projects through the discovery processScientific expertise in immuno-oncology including previous experience with characterization and preclinical development of T and/or NK cell engagersStrong verbal and written communication skillsLeadership experience and capabilities including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impactDemonstrated success in team management of PhD and non-PhD level scientists, in particular lab based colleaguesCandidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.Relocation support available.Work Location Assignment: On Premise.

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