Sarepta Therapeutics
Associate Director, Research Partnerships Group
Sarepta Therapeutics, Cambridge, Massachusetts, us, 02140
Why Sarepta? Why Now?The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.What Sarepta OffersAt Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:Physical and Emotional WellnessFinancial WellnessSupport for CaregiversFor a full list of our comprehensive benefits, see our website:
https://www.sarepta.com/join-usThe Importance of the RoleThis is an exciting opportunity for a highly motivated and creative individual to impact multiple drug discovery programs in our research organization and play a central role in applying Sarepta's expertise to gene therapy and gene editing drug development. The successful candidate will be responsible for target discovery and validation efforts, characterization of mechanism of action for gene therapy and gene editing programs and coordination of projects from target discovery through preclinical proof of concept, IND filing, and support of phase I clinical development for programs.The Opportunity to Make a DifferenceProvide scientific expertise and guidance on discovery efforts across the research organization. Experience in Neuromuscular, cardiovascular or CNS therapeutic areas is desirable.Manage communications and build relationships with key stakeholders including CROs and external collaborators.Serve as a subject matter expert on existing research agreements and strategic partnerships.Serve as subject matter expert to support Business Development diligence efforts.Participate as a key member of the Sarepta scientific leadership team in defining the scientific strategy of the gene therapy division programs.Design preclinical in vivo proof of concept, dose-escalation and IND-enabling studies and ensure successful execution as study director.Successfully lead multiple drug discovery programs from the early drug discovery phase into clinical development.Work with scientific leadership team to ensure strategic plans align with corporate goals and long-term company plans.Identify and apply state-of-the-art technologies and best practices to improve operational efficiency.Author relevant sections of clinical documents pertaining to but not limited to mechanism of action and translational assays (e.g. Clinical Protocols, Informed Consent, Clinical Study Reports, Investigator Brochures) and documentation for submission to regulatory agencies.Communicate effectively during regulatory interactions as a subject matter expert.More about YouPh.D. in a relevant discipline with 8+ years of experience and at least 3 years in neuromuscular disease and/or CNS therapeutic areas in a gene therapy biotech or pharma environment.In-depth knowledge and hands-on expertise of viral vector design and optimization,
in vitro
disease models,
in vivo
pharmacology and preclinical development.The successful candidate must have strong leadership skills, and be able to work independently as well as within multi-disciplinary project teams.Excellent interpersonal skills with a proven record of empowering world class science and energizing teams.What Now?We're always looking for solution-oriented, critical thinkers. So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.#LI-Remote #LI-TD1 This position is remote. However, you will be expected to work on site at one of Sarepta's facilities in the United States and/or attend Company-sponsored in-person events from time to time.The targeted salary range for this position is $156,000 - $195,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
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https://www.sarepta.com/join-usThe Importance of the RoleThis is an exciting opportunity for a highly motivated and creative individual to impact multiple drug discovery programs in our research organization and play a central role in applying Sarepta's expertise to gene therapy and gene editing drug development. The successful candidate will be responsible for target discovery and validation efforts, characterization of mechanism of action for gene therapy and gene editing programs and coordination of projects from target discovery through preclinical proof of concept, IND filing, and support of phase I clinical development for programs.The Opportunity to Make a DifferenceProvide scientific expertise and guidance on discovery efforts across the research organization. Experience in Neuromuscular, cardiovascular or CNS therapeutic areas is desirable.Manage communications and build relationships with key stakeholders including CROs and external collaborators.Serve as a subject matter expert on existing research agreements and strategic partnerships.Serve as subject matter expert to support Business Development diligence efforts.Participate as a key member of the Sarepta scientific leadership team in defining the scientific strategy of the gene therapy division programs.Design preclinical in vivo proof of concept, dose-escalation and IND-enabling studies and ensure successful execution as study director.Successfully lead multiple drug discovery programs from the early drug discovery phase into clinical development.Work with scientific leadership team to ensure strategic plans align with corporate goals and long-term company plans.Identify and apply state-of-the-art technologies and best practices to improve operational efficiency.Author relevant sections of clinical documents pertaining to but not limited to mechanism of action and translational assays (e.g. Clinical Protocols, Informed Consent, Clinical Study Reports, Investigator Brochures) and documentation for submission to regulatory agencies.Communicate effectively during regulatory interactions as a subject matter expert.More about YouPh.D. in a relevant discipline with 8+ years of experience and at least 3 years in neuromuscular disease and/or CNS therapeutic areas in a gene therapy biotech or pharma environment.In-depth knowledge and hands-on expertise of viral vector design and optimization,
in vitro
disease models,
in vivo
pharmacology and preclinical development.The successful candidate must have strong leadership skills, and be able to work independently as well as within multi-disciplinary project teams.Excellent interpersonal skills with a proven record of empowering world class science and energizing teams.What Now?We're always looking for solution-oriented, critical thinkers. So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.#LI-Remote #LI-TD1 This position is remote. However, you will be expected to work on site at one of Sarepta's facilities in the United States and/or attend Company-sponsored in-person events from time to time.The targeted salary range for this position is $156,000 - $195,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
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