Global Channel Management, Inc.
Scientist Antibody Discovery
Global Channel Management, Inc., San Francisco, California, United States, 94199
Scientist Antibody Discovery
needs significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques.
Scientist Antibody Discovery requires:PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with a minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+ years of research experience, BS with 10+ years of research experience in antibody or protein engineering.Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins.Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals.Highly motivated individual with exceptionally good organizational skills, and attention to details.Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design.Experience in NGS analysis for antibody discovery and engineering.Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry.
Scientist Antibody Discovery duties:Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display.Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits.Rank-order clones by affinity, in vitro potency, and early developability assessment.Execute sequence optimization of lead antibodies to improve developability and binding affinity.
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needs significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques.
Scientist Antibody Discovery requires:PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with a minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+ years of research experience, BS with 10+ years of research experience in antibody or protein engineering.Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins.Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals.Highly motivated individual with exceptionally good organizational skills, and attention to details.Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design.Experience in NGS analysis for antibody discovery and engineering.Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry.
Scientist Antibody Discovery duties:Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display.Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits.Rank-order clones by affinity, in vitro potency, and early developability assessment.Execute sequence optimization of lead antibodies to improve developability and binding affinity.
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