Cape Fox Shared Services
Animal Biologist
Cape Fox Shared Services, Bethesda, Maryland, us, 20811
Job Summary
The Animal Biologist will independently provide support services to satisfy the overall operational objectives of the National Heart, Lung and Blood Institute (NHLBI). The primary objective is to provide services and deliverables through the performance of support services.
The statements contained in this job description reflect general details as necessary to describe the principal functions of this job, the level of knowledge and skill typically required, and the scope of responsibility. It should not be considered an all-inclusive listing of work requirements. Employee may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise to balance the workload.
Essential Functions and Responsibilities
Identify, define and study the role of ADP-ribosylation in mammalian tissues.Define the components of the ART1 and ARHI complexes.Perform culture and transfecting of embryonic stem (ES) cells, and generation of targeted ES clones.Provide care and handling of laboratory animals according to the Animal Study Proposal.Collect different stages of mouse embryos.Generate chimeric mice by blastocyst microinjection or embryo aggregation.Transfer manipulated embryos into the oviducts or uteri of pseudo-pregnant foster mothers.Independently assess methods or procedures for use in experiments, make modifications and improvements to meet specific needs or to resolve problems.Maintain accurate, detailed records of laboratory experiments. Evaluate and interpret results for validity and scientific meaning.Prepare summaries of experiments and contribute to the evaluation and discussion of results.Collaborate with other members in the laboratory and contribute to overall team strategies.Assist in teaching others principles and methodologies.Contribute to the development of new capabilities and services in experimental design in the analysis of the effects of ADP-ribosylation both in vitro and in vivo, and the components ARTI and ARHI complexes.
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The Animal Biologist will independently provide support services to satisfy the overall operational objectives of the National Heart, Lung and Blood Institute (NHLBI). The primary objective is to provide services and deliverables through the performance of support services.
The statements contained in this job description reflect general details as necessary to describe the principal functions of this job, the level of knowledge and skill typically required, and the scope of responsibility. It should not be considered an all-inclusive listing of work requirements. Employee may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise to balance the workload.
Essential Functions and Responsibilities
Identify, define and study the role of ADP-ribosylation in mammalian tissues.Define the components of the ART1 and ARHI complexes.Perform culture and transfecting of embryonic stem (ES) cells, and generation of targeted ES clones.Provide care and handling of laboratory animals according to the Animal Study Proposal.Collect different stages of mouse embryos.Generate chimeric mice by blastocyst microinjection or embryo aggregation.Transfer manipulated embryos into the oviducts or uteri of pseudo-pregnant foster mothers.Independently assess methods or procedures for use in experiments, make modifications and improvements to meet specific needs or to resolve problems.Maintain accurate, detailed records of laboratory experiments. Evaluate and interpret results for validity and scientific meaning.Prepare summaries of experiments and contribute to the evaluation and discussion of results.Collaborate with other members in the laboratory and contribute to overall team strategies.Assist in teaching others principles and methodologies.Contribute to the development of new capabilities and services in experimental design in the analysis of the effects of ADP-ribosylation both in vitro and in vivo, and the components ARTI and ARHI complexes.
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