Flagship Pioneering
Pioneering Medicines Director / Senior Director, In Vitro Pharmacology
Flagship Pioneering, Cambridge, Massachusetts, us, 02140
What if...
We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?Pioneering Medicines
is dedicated to conceiving and developing a broad portfolio of life-changing treatments by leveraging and expanding the use of Flagship’s multiple bioplatforms and Flagship’s proprietary innovation process. By harnessing the power of Flagship’s first-in-category platforms, Pioneering Medicines creates and advances novel medicines, partnering with Flagship companies to accelerate the extension of their portfolios into new areas and show that the platform can be applied more broadly, thereby delivering benefits to more patients, sooner.With a highly experienced drug development team and access to the wide ecosystem of Flagship companies, Pioneering Medicines is well positioned to conceive new medicine ideas both internally and in collaboration with strategic partners and advance these assets through to significant value inflection. Pioneering Medicines currently has 11 programs ongoing with plans to have more than 15 programs in 2024.Position Summary:Pioneering Medicines is seeking a highly motivated and strategic In Vitro Pharmacology leader to support a growing portfolio of assets. This key leadership role will require an individual to direct and oversee in vitro pharmacology efforts, participating in drug discovery and early development activities. The role will involve functional accountability to support assets across a diverse range of modalities and therapeutic areas, including inflammation and metabolic diseases. The candidate will work in cross-functional teams leading and supporting the activities, delivering research leadership, and managing scientists. The successful candidate is expected to proactively build and maintain strong collaborations with Flagship Pioneering platform companies and large pharma partners. We are seeking individuals who are analytical, goal-oriented, and timeline-sensitive, while maintaining the highest of scientific and ethical standards. Strong communication skills and comfort working in a dynamic and cross-functional team environment are required.Responsibilities:Support projects across diverse therapeutic areas/modalities including inflammation and metabolic therapeutic areasServe as a Research Project Leader to develop research strategy and drive execution of drug discovery projectsIdentify and implement preclinical cell-based models that reflect patient pathology and develop assays to support in vitro characterization of lead small molecules, biologics, and genetic modalitiesDevelop in vitro pharmacology plans and budgets to progress lead molecules from hit-to-lead to DC and IND/CTALead scientific discussions with Flagship Platform companies and external pharmaceutical partnersLead a team of PhD and non-PhD scientists, including managersThis position is on-site/hybrid in Cambridge, MARequired Qualifications & ExperiencePh.D., in Biology, Biochemistry or related field12+ years of relevant pharmaceutical/biotechnology experienceExtensive experience in assay development and proficiency in drug discovery and development, including delivering data and documentation supporting IND/CTA regulatory filingsProven leadership and excellent mentorship skills, with experience in managing a team and leading programmatic matrix teamsScientific experience working in inflammation or metabolic drug discovery and development programsAbility and interest to work across multiple therapeutic areas and modalitiesAbility to effectively communicate complex scientific concepts and data to both scientific and non-scientific colleaguesPreferred QualificationsExperience performing scientific due diligence on assets and/or platform biotechsExperience working on cross-industry collaborationsAbout Flagship Pioneering:Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.Flagship Pioneering and our ecosystem companies are
committed to equal employment opportunity
regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
#J-18808-Ljbffr
We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?Pioneering Medicines
is dedicated to conceiving and developing a broad portfolio of life-changing treatments by leveraging and expanding the use of Flagship’s multiple bioplatforms and Flagship’s proprietary innovation process. By harnessing the power of Flagship’s first-in-category platforms, Pioneering Medicines creates and advances novel medicines, partnering with Flagship companies to accelerate the extension of their portfolios into new areas and show that the platform can be applied more broadly, thereby delivering benefits to more patients, sooner.With a highly experienced drug development team and access to the wide ecosystem of Flagship companies, Pioneering Medicines is well positioned to conceive new medicine ideas both internally and in collaboration with strategic partners and advance these assets through to significant value inflection. Pioneering Medicines currently has 11 programs ongoing with plans to have more than 15 programs in 2024.Position Summary:Pioneering Medicines is seeking a highly motivated and strategic In Vitro Pharmacology leader to support a growing portfolio of assets. This key leadership role will require an individual to direct and oversee in vitro pharmacology efforts, participating in drug discovery and early development activities. The role will involve functional accountability to support assets across a diverse range of modalities and therapeutic areas, including inflammation and metabolic diseases. The candidate will work in cross-functional teams leading and supporting the activities, delivering research leadership, and managing scientists. The successful candidate is expected to proactively build and maintain strong collaborations with Flagship Pioneering platform companies and large pharma partners. We are seeking individuals who are analytical, goal-oriented, and timeline-sensitive, while maintaining the highest of scientific and ethical standards. Strong communication skills and comfort working in a dynamic and cross-functional team environment are required.Responsibilities:Support projects across diverse therapeutic areas/modalities including inflammation and metabolic therapeutic areasServe as a Research Project Leader to develop research strategy and drive execution of drug discovery projectsIdentify and implement preclinical cell-based models that reflect patient pathology and develop assays to support in vitro characterization of lead small molecules, biologics, and genetic modalitiesDevelop in vitro pharmacology plans and budgets to progress lead molecules from hit-to-lead to DC and IND/CTALead scientific discussions with Flagship Platform companies and external pharmaceutical partnersLead a team of PhD and non-PhD scientists, including managersThis position is on-site/hybrid in Cambridge, MARequired Qualifications & ExperiencePh.D., in Biology, Biochemistry or related field12+ years of relevant pharmaceutical/biotechnology experienceExtensive experience in assay development and proficiency in drug discovery and development, including delivering data and documentation supporting IND/CTA regulatory filingsProven leadership and excellent mentorship skills, with experience in managing a team and leading programmatic matrix teamsScientific experience working in inflammation or metabolic drug discovery and development programsAbility and interest to work across multiple therapeutic areas and modalitiesAbility to effectively communicate complex scientific concepts and data to both scientific and non-scientific colleaguesPreferred QualificationsExperience performing scientific due diligence on assets and/or platform biotechsExperience working on cross-industry collaborationsAbout Flagship Pioneering:Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.Flagship Pioneering and our ecosystem companies are
committed to equal employment opportunity
regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
#J-18808-Ljbffr