Wyss Institute at Harvard University
Scientist I (68159BR)
Wyss Institute at Harvard University - Boston, Massachusetts, us, 02298
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Scientist I (68159BR)
role at
Wyss Institute at Harvard University
About Us:
The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground-breaking technologies into commercial products that solve big problems. We support risky research that universities, companies, and venture capital firms often avoid, preferring to tackle challenging projects. Discover our technologies, recent news, or watch our latest videos for more information.
Job Summary:
The Wyss Institute’s Brain Targeting Program (BTP), co-led by James Gorman, M.D., Ph.D., and Donald Ingber, M.D., Ph.D., develops brain delivery technologies to enable safer and more effective therapeutics for brain diseases. We are seeking a Scientist to support our brain shuttle target identification and validation platform, involving assay development, protein expression analysis, and transport validation.
Responsibilities:
Develop and optimize brain shuttle target identification and validation experiments.
Prepare samples for proteomics, including tissue homogenization and cell isolation, coordinating with mass spectrometry facilities.
Design and perform protein validation assays such as Western blot, ELISA, immunohistochemistry, and FACS; support in vitro and in vivo transport assays.
Analyze multi-omics datasets to prioritize targets for validation.
Mentor team members and interns, and possibly supervise technicians.
Present results internally and contribute to experimental strategies.
Collaborate effectively within and across teams, demonstrating scientific rigor and teamwork.
Qualifications:
Bachelor’s degree in neuroscience, biology, molecular biology, biochemistry, or related field.
At least four years of hands-on experience in proteomics, cell culture, rodent handling, and molecular/cellular techniques such as ELISA, Western blot, confocal imaging, and FACS.
Preferred Skills:
PhD in relevant fields is strongly preferred.
Experience with RNA-Seq, proteomics, microvessel isolation, biotinylation, and transport assays.
Proficiency with software such as Microsoft Office, R, Prism, flowJo.
Additional Information:
This in-person position is based in Boston. The role includes comprehensive benefits, professional development, and a supportive environment committed to diversity and inclusion. Offer contingent on medical evaluation.
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Scientist I (68159BR)
role at
Wyss Institute at Harvard University
About Us:
The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground-breaking technologies into commercial products that solve big problems. We support risky research that universities, companies, and venture capital firms often avoid, preferring to tackle challenging projects. Discover our technologies, recent news, or watch our latest videos for more information.
Job Summary:
The Wyss Institute’s Brain Targeting Program (BTP), co-led by James Gorman, M.D., Ph.D., and Donald Ingber, M.D., Ph.D., develops brain delivery technologies to enable safer and more effective therapeutics for brain diseases. We are seeking a Scientist to support our brain shuttle target identification and validation platform, involving assay development, protein expression analysis, and transport validation.
Responsibilities:
Develop and optimize brain shuttle target identification and validation experiments.
Prepare samples for proteomics, including tissue homogenization and cell isolation, coordinating with mass spectrometry facilities.
Design and perform protein validation assays such as Western blot, ELISA, immunohistochemistry, and FACS; support in vitro and in vivo transport assays.
Analyze multi-omics datasets to prioritize targets for validation.
Mentor team members and interns, and possibly supervise technicians.
Present results internally and contribute to experimental strategies.
Collaborate effectively within and across teams, demonstrating scientific rigor and teamwork.
Qualifications:
Bachelor’s degree in neuroscience, biology, molecular biology, biochemistry, or related field.
At least four years of hands-on experience in proteomics, cell culture, rodent handling, and molecular/cellular techniques such as ELISA, Western blot, confocal imaging, and FACS.
Preferred Skills:
PhD in relevant fields is strongly preferred.
Experience with RNA-Seq, proteomics, microvessel isolation, biotinylation, and transport assays.
Proficiency with software such as Microsoft Office, R, Prism, flowJo.
Additional Information:
This in-person position is based in Boston. The role includes comprehensive benefits, professional development, and a supportive environment committed to diversity and inclusion. Offer contingent on medical evaluation.
#J-18808-Ljbffr