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GlaxoSmithKline

Oligos Analytical Chemistry Team Leader

GlaxoSmithKline, Cambridge, Massachusetts, us, 02140


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USA - Massachusetts - CambridgePosted Date:

Oct 4 2024Are you passionate about analytical chemistry and eager to contribute to the discovery of novel oligonucleotide therapeutics? If so, we have the perfect opportunity for you.As the Team Leader, Oligonucleotide Analytical Chemistry, you and your team will play a pivotal role in the analysis and quality control of GSK’s pre-clinical therapeutic oligonucleotide pipeline. You will leverage advanced analytical chemistry techniques to accelerate GSK’s pre-clinical oligonucleotide pipeline and platform technology ambitions.This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:Lead and Innovate:

Establish and lead the oligonucleotide analytical team, collaborating cross-functionally to advance our pre-clinical portfolio and technology platforms. Hire, manage, coach, and develop a high-performing team.Be the Expert:

Serve as GSK’s subject matter expert on oligonucleotide analytical chemistry. Keep abreast of industry advancements, regulatory requirements, and competitor approaches in oligonucleotide analysis.Communicate Impact:

Provide regular updates and address challenges to stakeholders at all levels across GSK. Contribute to patents, publications, posters, and presentations, showcasing our scientific advancements.Standardize Excellence:

Develop and maintain standard operating procedures (SOPs) for oligonucleotide and monomer analysis and characterization to ensure high-quality, reproducible results.Foster Quality:

Partner with the oligonucleotide chemistry team to ensure accountability and excellence in oligonucleotide and conjugate synthesis.Collaborate Externally:

Support partnerships with external entities and manage relationships with CROs as needed.Why you?

Basic Qualifications:We are looking for professionals with these required skills to achieve our goals:BS/MS with 5+ years or Ph.D. with 2+ years of experience in the analysis of oligonucleotides, including 2+ years of experience managing laboratory scientists.Experience in modern analytical and quality control methods as applied to therapeutic oligonucleotides. Experience with small molecules/biologics, monomers, conjugates, and relevant formulations thereof.Leadership experience, including training, developing, and managing talent and the ability to build, motivate, and inspire diverse high-performing teams. Prior experience of establishing an oligonucleotide analytical laboratory.Strong analytical chemistry expertise in solving analytical challenges in the field of therapeutic oligonucleotides.Preferred Qualifications:If you have the following characteristics, it would be a plus:Proven effective communication and negotiation skills suitable for a wide range of audiences, from laboratory analysts to senior management.Demonstrated effective organizational skills, including the ability to set, prioritize, and achieve research goals.Excellent scientific and analytical skills, with a demonstrable ability to multitask, prioritize, and drive projects to conclusion.A demonstrable understanding of RNA biology and contemporary oligonucleotide screening technologies.Ability to work effectively with a team of multidisciplinary experts including biology, chemistry, safety assessment, computational sciences, clinical scientists, translational scientists, and others.#LI-GSK

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