GlaxoSmithKline
Senior Scientist- High Throughput Automation
GlaxoSmithKline, Collegeville, Pennsylvania, United States, 19426
Site Name:
USA - Pennsylvania - Upper ProvidencePosted Date:
Oct 2 2024GlaxoSmithKline, a global pharmaceutical company, has committed to drive innovation by expanding a state-of-the-art automation laboratory. The use of automated high-throughput robotic laboratory platforms in research and development improves efficiency in the drug development process. The ongoing vision of laboratory automation is one where implementation:Enables our scientists to minimize resource requirements and maximize the experimental design space to rapidly make better-informed decisions.Drives the reduction in experimental turnaround times by utilizing knowledge and capabilities of automation technology to deliver more robust workflows to increase quality development of medicines.As part of this strategy, a multi-million-dollar robotic laboratory has been built in Collegeville PA to support the development, evaluation, and optimization of drug products. This team actively drives how automation is applied to accelerate the medicine pipeline, ultimately delivering quality, life-saving medicine to patients, faster. As such, the purpose of the role is to successfully utilize the automation assets for rapid screening and/or development to reduce design selection risks and enhance product design across all phases of development.Working in a matrix team, develop appropriate automation protocols to meet the needs of the scientists, analysts, chemists, engineers and formulators across the R&D organization.Optimize workflow design by successfully utilizing a range of specialized robots to run key pharmaceutical screening such as drug solubility, stability and crystallization, enhancing drug product design across all phases of development.Gain a deep understanding of early pharmaceutical testing and applying automation to accelerate drug candidates from discovery to clinical trials.Explore a wide range of experimental procedures and projects by working on new pharmaceutical assets on a weekly basis.Apply appropriate analytical techniques such as Liquid Chromatography, FT-Raman, Microscopy and X-Ray Powder Diffraction to explore the physical properties of materials, excipients of pharmaceutical relevance, and chemical reactions of synthetic intermediates.Participate on multidisciplinary project teams and collaborate with colleagues to define and implement development strategies according to project timelines.Organize, evaluate, and present data in an effective and scientific manner using advanced software visualization tools.Contribute to the development of new analytical and data automation approaches and knowledge within the global automation organization.Why you?Basic Qualifications:We are looking for professionals with these required skills to achieve our goals:Bachelor's degree in chemistry, engineering, or related life sciences applications with 2+ years industry experience.2+ years Chromatography experience and tools (i.e. HPLC)Preferred Qualifications:If you have the following characteristics, it would be a plus:Master's degree in chemistry, engineering, or related life sciences applicationsDemonstrated ability to interface with multiple internal and external groups to successfully deliver projects.Broad knowledge base and active member of the analytical or formulation community.High learning agility with the ability and willingness to deal effectively with first-time situations or changing conditions.Knowledge and experience with statistical design of experiments and analysis of results.Knowledge of solid-state analytical methods such as microscopy, FT-Raman, and XRPD.Demonstrated ability to integrate, test, and troubleshoot analytical instrumentation such as HPLC & UPLC.Proven ability to translate scientific processes to new platforms and to identify new application areas.Interest in development of end-to-end analytical and data automation processes.Proven ability to design experimental workflows to optimize/improve ways of working that address specific analytical needs of stakeholders.Why GSK?Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:Operating at pace and agile decision-making – using evidence and applying judgement to balance pace, rigour and risk.Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.Continuously looking for opportunities to learn, build skills and share learning.Sustaining energy and well-beingBuilding strong relationships and collaboration, honest and open conversations.Budgeting and cost-consciousness
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USA - Pennsylvania - Upper ProvidencePosted Date:
Oct 2 2024GlaxoSmithKline, a global pharmaceutical company, has committed to drive innovation by expanding a state-of-the-art automation laboratory. The use of automated high-throughput robotic laboratory platforms in research and development improves efficiency in the drug development process. The ongoing vision of laboratory automation is one where implementation:Enables our scientists to minimize resource requirements and maximize the experimental design space to rapidly make better-informed decisions.Drives the reduction in experimental turnaround times by utilizing knowledge and capabilities of automation technology to deliver more robust workflows to increase quality development of medicines.As part of this strategy, a multi-million-dollar robotic laboratory has been built in Collegeville PA to support the development, evaluation, and optimization of drug products. This team actively drives how automation is applied to accelerate the medicine pipeline, ultimately delivering quality, life-saving medicine to patients, faster. As such, the purpose of the role is to successfully utilize the automation assets for rapid screening and/or development to reduce design selection risks and enhance product design across all phases of development.Working in a matrix team, develop appropriate automation protocols to meet the needs of the scientists, analysts, chemists, engineers and formulators across the R&D organization.Optimize workflow design by successfully utilizing a range of specialized robots to run key pharmaceutical screening such as drug solubility, stability and crystallization, enhancing drug product design across all phases of development.Gain a deep understanding of early pharmaceutical testing and applying automation to accelerate drug candidates from discovery to clinical trials.Explore a wide range of experimental procedures and projects by working on new pharmaceutical assets on a weekly basis.Apply appropriate analytical techniques such as Liquid Chromatography, FT-Raman, Microscopy and X-Ray Powder Diffraction to explore the physical properties of materials, excipients of pharmaceutical relevance, and chemical reactions of synthetic intermediates.Participate on multidisciplinary project teams and collaborate with colleagues to define and implement development strategies according to project timelines.Organize, evaluate, and present data in an effective and scientific manner using advanced software visualization tools.Contribute to the development of new analytical and data automation approaches and knowledge within the global automation organization.Why you?Basic Qualifications:We are looking for professionals with these required skills to achieve our goals:Bachelor's degree in chemistry, engineering, or related life sciences applications with 2+ years industry experience.2+ years Chromatography experience and tools (i.e. HPLC)Preferred Qualifications:If you have the following characteristics, it would be a plus:Master's degree in chemistry, engineering, or related life sciences applicationsDemonstrated ability to interface with multiple internal and external groups to successfully deliver projects.Broad knowledge base and active member of the analytical or formulation community.High learning agility with the ability and willingness to deal effectively with first-time situations or changing conditions.Knowledge and experience with statistical design of experiments and analysis of results.Knowledge of solid-state analytical methods such as microscopy, FT-Raman, and XRPD.Demonstrated ability to integrate, test, and troubleshoot analytical instrumentation such as HPLC & UPLC.Proven ability to translate scientific processes to new platforms and to identify new application areas.Interest in development of end-to-end analytical and data automation processes.Proven ability to design experimental workflows to optimize/improve ways of working that address specific analytical needs of stakeholders.Why GSK?Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:Operating at pace and agile decision-making – using evidence and applying judgement to balance pace, rigour and risk.Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.Continuously looking for opportunities to learn, build skills and share learning.Sustaining energy and well-beingBuilding strong relationships and collaboration, honest and open conversations.Budgeting and cost-consciousness
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