Logo
St. Jude Children's Research Hospital (St. Jude)

Scientist / Senior Scientist Opportunity in St. Jude's Center for Advanced Genom

St. Jude Children's Research Hospital (St. Jude), Memphis, Tennessee, us, 37544


St. Jude Children's Research Hospital seeks a Scientist or Senior Scientist to join our Center for Advanced Genome Engineering (CAGE).The World’s Brightest Minds Always InnovateAt

St. Jude Children’s Research Hospital , we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities, state-of-the-art technologies, and extraordinary support for your research to ensure scientific progress is never halted from a lack of resources. At St. Jude, you will be part of a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve.This is an exciting opportunity for a

Scientist or Senior Scientist

to join our

Center for Advanced Genome Engineering

(CAGE).The CAGE has three missions:Facilitate investigator-initiated genome editing projects using CRISPR-Cas9.Perform independent R&D to evaluate and develop new genome editing techniques.Assist the gene and cell therapy programs at St. Jude Children’s Research Hospital.The

Shondra Pruett-Miller

laboratory offers a strong team-based environment where you will work collaboratively with other investigators across the institution to support their research needs and develop and improve genome engineering technologies.In this position, you will lead the Custom CRISPR Library service. You will stay up to date on current CRISPR screening technologies and adapt and incorporate them into current workflows to aid St. Jude investigators with their research. Duties will also include designing, cloning, and analyzing CRISPR libraries designed for knockout, inhibition, and activation screens. You will help fellow team members with their own designs and analyses. Your experience will also be used for developing and implementing bioinformatic workflows which aid CAGE lab members in CRISPR design and NGS analysis.Successful candidates should display competencies in the following areas:Understanding of and experience with molecular biology techniques including DNA and RNA extractions, PCR, and plasmid cloning.In-depth knowledge and experience with CRISPR screens and analysis.Excellent verbal and written communication skills.Creative and self-motivated.Experience with programming in Python or other coding languages is a plus.Experience with liquid handling robots is a plus.Comfortable in a Linux environment and working on a cluster.Comfortable working independently and as part of a team.Ability to prioritize work based on need.Ability to track and execute multiple projects at once.Experience with Next-Generation Sequencing analysis is a plus.Minimum Education and/or Training:Bachelor's degree in a relevant scientific area is required.Minimum Experience:Senior Scientist:Ten (10) years of relevant post-degree work experience is required with a Bachelor's degree.Eight (8) years of relevant post-degree work experience is required with a Master's degree.Six (6) years of relevant post-degree work experience is required with a PhD.Scientist:Seven (7) years of relevant post-degree work experience is required with a Bachelor's degree.Five (5) years of relevant post-degree work experience is required with a Master's degree.Three (3) years of relevant post-degree work experience is required with a PhD.

#J-18808-Ljbffr