Alnylam Pharmaceuticals
Associate Scientist I, RNAi Discovery
Alnylam Pharmaceuticals, Cambridge, Massachusetts, us, 02140
This role is considered On-Site.OverviewThe experienced Research Associate Scientist I, with a background in in vitro screening, will be part of our dynamic, fast-paced and interdisciplinary lead development team. Our mission is to advance novel RNAi therapeutic programs from target discovery through lead candidate selection. The Associate Scientist I will be technically skilled in molecular and/or cell biology, and bring a rigorous, analytical approach to research.This position is
onsite
and will be primarily located in Cambridge, MA.Key ResponsibilitiesPerform cell culture (iPSCs, primary cells, immortalized cell lines) to support the research needs of the group and high-throughput screening of siRNAs using qPCR and a variety of cell-based assays.Execute day-to-day operations for in vitro screening, including sample preparation & QC.Maintain sample tracking & records.Support lab maintenance including equipment operation & maintenance, reagent inventory, and reagent preparation.Utilize instrumentation and robotics to aid in high throughput screening.Adapt well to the changing platform needs, in workflow, projects, and other tasks as required by the platform.Perform other duties as assigned by manager.QualificationsGED/HS diploma required; 2- or 4-year college degree in related field preferred.Experience in tissue culture and purification/quantification of nucleic acids, including qPCR.The candidate should be intensely detail-oriented, highly motivated, and willing to learn.Excellent interpersonal skills with the ability to work well with others in a dynamic and highly collaborative environment.Must be able to work in a standing position for prolonged periods of time while performing repetitive motion tasks.Ability to read and interpret documents such as safety rules, operating and maintenance instructions, specifications, and procedure manuals.Mathematics skills adequate for calculating dilutions and dose projections.Basic computer skills and proficiency in Microsoft Outlook, Word, PowerPoint, and Excel required.About Alnylam:
Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.Our culture:
Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people. These values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and the UK - among others.At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.
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onsite
and will be primarily located in Cambridge, MA.Key ResponsibilitiesPerform cell culture (iPSCs, primary cells, immortalized cell lines) to support the research needs of the group and high-throughput screening of siRNAs using qPCR and a variety of cell-based assays.Execute day-to-day operations for in vitro screening, including sample preparation & QC.Maintain sample tracking & records.Support lab maintenance including equipment operation & maintenance, reagent inventory, and reagent preparation.Utilize instrumentation and robotics to aid in high throughput screening.Adapt well to the changing platform needs, in workflow, projects, and other tasks as required by the platform.Perform other duties as assigned by manager.QualificationsGED/HS diploma required; 2- or 4-year college degree in related field preferred.Experience in tissue culture and purification/quantification of nucleic acids, including qPCR.The candidate should be intensely detail-oriented, highly motivated, and willing to learn.Excellent interpersonal skills with the ability to work well with others in a dynamic and highly collaborative environment.Must be able to work in a standing position for prolonged periods of time while performing repetitive motion tasks.Ability to read and interpret documents such as safety rules, operating and maintenance instructions, specifications, and procedure manuals.Mathematics skills adequate for calculating dilutions and dose projections.Basic computer skills and proficiency in Microsoft Outlook, Word, PowerPoint, and Excel required.About Alnylam:
Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.Our culture:
Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people. These values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and the UK - among others.At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.
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