Pfizer, S.A. de C.V
Scientist - Upstream Process Development
Pfizer, S.A. de C.V, Andover, Massachusetts, us, 05544
Scientist - Upstream Process Development
We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.A Scientist (R3) position is available in the Upstream Process Development group within the Bioprocess R&D organization. The successful applicant will join a team of scientists and engineers focused on developing and optimizing manufacturing processes for recombinant proteins and mRNAs for early- and late-phase human clinical trials. In this role, the candidate will be responsible for designing and executing laboratory experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes. The work will also involve working with pilot, clinical, and commercial production facilities to ensure accurate technology transfer, successful large-scale production and associated regulatory filing activities. The candidate may also be involved in cutting edge technology development projects that seek to improve production processes and control strategies leveraging various process analytical technologies.How You Will Achieve ItDesign and execute experiments in appropriate scale-down models such as shake flasks and bioreactors in an effort to develop robust, high yield, and scalable manufacturing processes.Serve as upstream tech lead; ensure accurate tech transfer to pilot and GMP manufacturing facilities; provide technical support during manufacturing campaign.Timely and accurately document data in electronic lab notebooks; author technical reports and contribute to relevant sections of regulatory submissions such as IND and BLA.Participate and contribute to discussions in lab and project team meetings on design of experiments and interpretation of data.Contribute to safe, efficient, and harmonious lab environment; strong lab citizen and collaborative team player.Occasionally work over the weekend to passage flasks, sample bioreactors or perform other essential tasks.QUALIFICATIONSMust HaveBachelor’s degree with 5-8 years’ industrial experience or Master degree with 3-6 years industrial experience in Chemical/Biochemical Engineering, Biotechnology, Microbiology or a relevant field.Significant experience with sophisticated lab instruments such as bioreactor systems and analytical equipment.Strong mammalian cell culture expertise required.Self-motivated, organized, and excellent attention to details.Excellent oral and written communication skills.Ability to adapt in a fast-paced environment with shifting priorities.Nice To HaveExperience with high-throughput instrument such as ambr15, ambr250, and Tecan liquid handler.Knowledge pertaining to in vitro transcription for mRNA synthesis or hands-on experience with molecular biology techniques.Experience with developing and implementing process analytical technologies such as Raman spectroscopy and biocapacitance.Proficiency with multi-variate data analysis techniques.PHYSICAL/MENTAL REQUIREMENTSLifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTSMay require occasional work on the weekend for essential tasks.May need to travel occasionally to attend internal meetings or external conferences.Other Job DetailsWork Location Assignment: On PremiseThe annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.A Scientist (R3) position is available in the Upstream Process Development group within the Bioprocess R&D organization. The successful applicant will join a team of scientists and engineers focused on developing and optimizing manufacturing processes for recombinant proteins and mRNAs for early- and late-phase human clinical trials. In this role, the candidate will be responsible for designing and executing laboratory experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes. The work will also involve working with pilot, clinical, and commercial production facilities to ensure accurate technology transfer, successful large-scale production and associated regulatory filing activities. The candidate may also be involved in cutting edge technology development projects that seek to improve production processes and control strategies leveraging various process analytical technologies.How You Will Achieve ItDesign and execute experiments in appropriate scale-down models such as shake flasks and bioreactors in an effort to develop robust, high yield, and scalable manufacturing processes.Serve as upstream tech lead; ensure accurate tech transfer to pilot and GMP manufacturing facilities; provide technical support during manufacturing campaign.Timely and accurately document data in electronic lab notebooks; author technical reports and contribute to relevant sections of regulatory submissions such as IND and BLA.Participate and contribute to discussions in lab and project team meetings on design of experiments and interpretation of data.Contribute to safe, efficient, and harmonious lab environment; strong lab citizen and collaborative team player.Occasionally work over the weekend to passage flasks, sample bioreactors or perform other essential tasks.QUALIFICATIONSMust HaveBachelor’s degree with 5-8 years’ industrial experience or Master degree with 3-6 years industrial experience in Chemical/Biochemical Engineering, Biotechnology, Microbiology or a relevant field.Significant experience with sophisticated lab instruments such as bioreactor systems and analytical equipment.Strong mammalian cell culture expertise required.Self-motivated, organized, and excellent attention to details.Excellent oral and written communication skills.Ability to adapt in a fast-paced environment with shifting priorities.Nice To HaveExperience with high-throughput instrument such as ambr15, ambr250, and Tecan liquid handler.Knowledge pertaining to in vitro transcription for mRNA synthesis or hands-on experience with molecular biology techniques.Experience with developing and implementing process analytical technologies such as Raman spectroscopy and biocapacitance.Proficiency with multi-variate data analysis techniques.PHYSICAL/MENTAL REQUIREMENTSLifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTSMay require occasional work on the weekend for essential tasks.May need to travel occasionally to attend internal meetings or external conferences.Other Job DetailsWork Location Assignment: On PremiseThe annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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