Penn Foster
Senior Scientist
Penn Foster, Andover, Massachusetts, us, 05544
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will Achieve
Deliver results in a fast-paced matrix-oriented setting, be a contributor to key process purification steps and hold responsibility for various downstream process development activities. This advertised role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, therapeutic proteins, and polysaccharides in commercial operations and late-stage clinical development. The candidate will work across downstream purification functions, projects, and global sites.How You Will Achieve It
The MSAT downstream purification group is responsible for providing support to the upstream team, as well as downstream development purification/optimization, mRNA drug substance process activities and providing support to routine manufacturing operations.Candidate should have in-depth scientific knowledge and experience in a wide array of techniques such as mRNA Drug Substance process, UF/DF, Column Chromatograph, and ideally familiar with standard downstream equipment, e.g. AKTAs.Development and qualification of purification techniques.Ensure the proper and timely execution in all aspects of purification processing to support group activities.Perform scale-down purifications of biologics using precipitation, depth filtration, ultrafiltration and chromatography with the assistance of lab supervisor/designee.Qualified candidates will serve as a purification and biochemistry resource for the department and project teams, while proactively keeping historical product knowledge and experience.QUALIFICATIONS
Must Have
Applicant must have a High School Diploma (or Equivalent) and 10 years of relevant experience OR an associates degree with 8 years of experience OR a bachelors with at least 5 years of experience OR Masters Degree with more than 3 years of experience, OR a PhD with 0+ years of experience.Demonstrated technical writing skills and effective communication are strongly desired.Experience with technologies focused on mRNA drug substance process such as In-vitro transcription reactions, Enzyme based process and purification of biomolecules such as, Enzymatic reactions, AKTA, UF/DF, Column Chromatography.Nice to Have
Knowledge and experience in Critical Quality Attributes (CQA) principles and practices and product specifications and specification setting.Demonstrated technical skills and scientific expertise in purification process development and troubleshooting.Familiarity with mRNA Lipid nano particle formulation and Final Drug Product (FDP) processes.Experience with Microsoft Office, Excel, Word, etc.Change agile, functional in a fast-paced team environment where multi-tasking required.Enthusiastic about communicating to a broad range of stakeholders (from novices to experts) and seeking agreement in complex situations.Curiosity about seeking and applying current relevant scientific literature.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Position is first shift Monday through Friday. Some Holiday and off hour support may be required to support review and/or testing needs.Work Location Assignment: On Premise
OTHER JOB DETAILS
Last Date to Apply for Job: August 10, 2023Referral Bonus Eligibility: YESEligible for Relocation Package: NORelocation assistance may be available based on business needs and/or eligibility.EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
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Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will Achieve
Deliver results in a fast-paced matrix-oriented setting, be a contributor to key process purification steps and hold responsibility for various downstream process development activities. This advertised role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, therapeutic proteins, and polysaccharides in commercial operations and late-stage clinical development. The candidate will work across downstream purification functions, projects, and global sites.How You Will Achieve It
The MSAT downstream purification group is responsible for providing support to the upstream team, as well as downstream development purification/optimization, mRNA drug substance process activities and providing support to routine manufacturing operations.Candidate should have in-depth scientific knowledge and experience in a wide array of techniques such as mRNA Drug Substance process, UF/DF, Column Chromatograph, and ideally familiar with standard downstream equipment, e.g. AKTAs.Development and qualification of purification techniques.Ensure the proper and timely execution in all aspects of purification processing to support group activities.Perform scale-down purifications of biologics using precipitation, depth filtration, ultrafiltration and chromatography with the assistance of lab supervisor/designee.Qualified candidates will serve as a purification and biochemistry resource for the department and project teams, while proactively keeping historical product knowledge and experience.QUALIFICATIONS
Must Have
Applicant must have a High School Diploma (or Equivalent) and 10 years of relevant experience OR an associates degree with 8 years of experience OR a bachelors with at least 5 years of experience OR Masters Degree with more than 3 years of experience, OR a PhD with 0+ years of experience.Demonstrated technical writing skills and effective communication are strongly desired.Experience with technologies focused on mRNA drug substance process such as In-vitro transcription reactions, Enzyme based process and purification of biomolecules such as, Enzymatic reactions, AKTA, UF/DF, Column Chromatography.Nice to Have
Knowledge and experience in Critical Quality Attributes (CQA) principles and practices and product specifications and specification setting.Demonstrated technical skills and scientific expertise in purification process development and troubleshooting.Familiarity with mRNA Lipid nano particle formulation and Final Drug Product (FDP) processes.Experience with Microsoft Office, Excel, Word, etc.Change agile, functional in a fast-paced team environment where multi-tasking required.Enthusiastic about communicating to a broad range of stakeholders (from novices to experts) and seeking agreement in complex situations.Curiosity about seeking and applying current relevant scientific literature.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Position is first shift Monday through Friday. Some Holiday and off hour support may be required to support review and/or testing needs.Work Location Assignment: On Premise
OTHER JOB DETAILS
Last Date to Apply for Job: August 10, 2023Referral Bonus Eligibility: YESEligible for Relocation Package: NORelocation assistance may be available based on business needs and/or eligibility.EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
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