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University of Oklahoma Health Sciences Center

NIH-funded post-doctoral research fellow position in pancreatic cancer metabolis

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States, 73116


NIH-funded post-doctoral research fellow position in pancreatic cancer metabolism

The Pankaj Singh lab at the newly established Department of Oncology Science and the NCI-designated OU Health Stephenson Cancer Center is recruiting a postdoctoral researcher to join on an NIH/NCI-funded study on

pancreatic cancer metabolism.

The research project involves investigating signal transduction and metabolic alterations in pancreatic cancer cells, tumor-stromal crosstalk, therapy resistance, metastasis, and immunometabolism, using cutting-edge technologies and multi-omics platforms.

A successful postdoctoral candidate should have a Ph.D. in the relevant field with a strong theoretical background in basic biochemistry and molecular biology and/or human physiology. The candidate should be well versed with basic molecular biology and cell culture techniques. The project also involves utilizing cell line, organoid or mouse models of pancreatic cancer (PDX models and genetically engineered models). Some LC-MS/MS, bioinformatics, and small-animal research experience is preferred but not required.

More details about our work can be found in some of our recent publications ( Cancer Cell

2017 32(1):71-87;

JEM

2020 217 (7):e20190745;

Immunity

2019 50(3):576-590;

Gastroenterology

2021 Jul 8:S0016-5085(21)03159-0;

Nature Reviews Cancer

2023 Mar 27:1-20;

PNAS

2024 Apr 2;121(14);

Cancer Discovery

2024, 14(1):176-193;

Elife

2024 Jul 8;12:RP87292;

Nature Cell Biology

2024 Apr;26(4):613-627).

Our state-of-the art research program utilizes multi-omics approaches, including metabolomics, spatial metabolomics, sc-RNA-seq, epigenomics, and proteomics. Our program is well-funded by NCI, with multiple R01 grants and U54 grant on acquired therapy resistance in pancreatic cancer.

The Singh lab is a friendly and welcoming place with great excitement for cancer research. We plan to complete the recruitment process soon.

Interested candidates should submit their CV directly at

Onc-Sci@ouhsc.edu .

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