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Cogent Scientific

Expert Pharma Biochemist

Cogent Scientific, San Francisco, California, United States, 94199


Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to partner in the global effort to improve lives through innovative science with an experienced workforce. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation. . Cogent Scientific offers competitive pay, attractive benefits, and an exciting work environment. We aim to recruit the best people who stand out among their peers and embody our Core Values:

C

lient Focused: We only succeed when our clients succeed.

O

utstanding: We deliver meticulous results through outstanding performance.

G

ood: We act ethically and morally.

E

mployee-Centric: We honor and support our employees.

N

imble: We are prepared to adapt in an ever-changing industry.

T

eam-Oriented: We collaborate with each other and with our clients.

We currently have a role available for an Experienced Pharma Biochemist.

Job duties include, but are not limited to:

Working with discovery, bioconjugation and protein engineering teams to independently design and execute experiments for screening and characterizing biologicals comprised of antibodies, antibody-drug conjugates (ADCs), and other modalities, created for treatment of several oncological indications

Employing various analytical and biophysical techniques to provide comprehensive characterization of hits, leads and candidate molecules at various stages of discovery/development

Utilizing surface plasmon resonance (SPR) and Biolayer Interferometry (BLI) to characterize the kinetics and affinity of antibody/antigen interactions, epitope bins of antibodies, and blocking of receptor ligand interactions by antibodies.

Characterizing protein stability, purity and quality using a variety of techniques, such as dynamic light scattering (DLS), static light scattering (SLS), capillary isoelectric focusing (cIEF), differential scanning fluorimetry (DSF), size exclusion chromatography (SEC), ion exchange chromatography (IEX), CE-SDS, and SDS-PAGE.

Interacting and collaborating with other teams across the company to provide biophysical solutions; efficiently analyze, collate, and disseminate data to deliver results to teams in a timely manner consistent with project timelines.

Clearly documenting experiments and results in electronic lab notebook entries.

Presenting periodic updates and reporting to senior management to influence strategic research decisions and operations.

Job requirements include, but are not limited to:

PhD in Biochemistry, Chemistry or related field with 1-3 years of laboratory experience outside of academia.

MS with 5+ years of experience or BS with 8+ years of experience will also be considered.

Thorough understanding of the theory of above-mentioned techniques.

Excellent communication skills – verbal and written.

Works well both within a team and as an individual.

Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.

The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

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