Dren Bio, Inc.
Senior Senior Research Associate, Oncology Research
Dren Bio, Inc., Foster City, California, United States, 94420
Senior Research Associate, Oncology Research
About the Company:
Dren Bio (the "Company") is a privately held, clinical stage biopharmaceutical company focused on developing therapeutic antibodies for the treatment of cancer, autoimmune and other serious diseases. The Company's management team and scientific advisors have profound expertise covering the discovery and development of specially engineered antibodies. Dren Bio's pipeline encompasses a multitude of programs from its two distinct, wholly-owned technologies. The Company's lead development candidate, DR-01, induces antibody-mediated killing of a specific cell type known to play a key role in various hematologic malignancies and autoimmune disorders.Function:
Level:
Senior Research AssociateLocation:
Foster City, CAReporting Manager:
Principal Scientist, Oncology ResearchAbout the Opportunity:
Dren Bio is seeking a highly talented and motivated Senior Research Associate to support our oncology efforts for the treatment of solid tumors. The ideal candidate should have work experience in an industrial setting and have a basic background of immunology and/or cell biology with strong technical experience. The candidate will work with a cross-functional team of scientists (immunologists, cell biologists, biochemists, and protein engineers) to advance research-stage programs into early clinical development. The candidate will perform in vitro and ex vivo studies to assess efficacy of our novel therapeutic agents and elucidate their impact on myeloid cell functions within the tumor microenvironment.Role and Responsibilities:
Perform in vitro/ex vivo experiments to determine efficacy and MOA of therapeutic antibodies.Work collaboratively with other researchers to advance various therapeutic antibodies in different cancer indications.Specific tasks include recombinant cell line engineering, cell surface receptor quantification by flow, primary and cancer cell culture, isolation of immune cells from human blood, animal or human tissue processing, multi-color flow cytometry for immuno-phenotyping, cytokine profiling by MSD or Luminex, ADCC or ADCP assays using Incucyte and flow cytometry, DNA/RNA extraction for gene expression studies, various cellular assays (IP, western blot, and IF).Meticulous record-keeping of scientific data, methods, and study designs.Education, Experience and Qualification Requirements:
BA/BS or MS in a biology-related discipline with approximately 4+ years of experience in biopharmaceutical industry, or a combination of 4+ years of industrial and academic experience.Core Competencies, Knowledge and Skill Requirements:
Extensive experience in culturing variety of cancer cell lines including lymphoid & myeloid derived cell lines and primary cells.Experience with flow cytometry-based methods for characterizing cell surface expression.Well-versed in various data processing and analysis software (e.g. FlowJo, Prism, ImageJ).Detail-oriented, highly organized, and able to multi-task with multiple assignments.Strong written and verbal communication skills.Ability to work in a fast-paced environment and the flexibility to align daily work with project needs.Ability to set goals and prioritize tasks and resources to achieve superior work quality and efficiency.Salaries, Benefits and Other Employee Perks:
Dren Bio strongly believes in investing in, and rewarding, its employees. This philosophy is embodied in the Company’s total rewards program, which includes competitive cash compensation, equity incentive awards, and employer sponsored benefit offerings. The base pay range for this position at commencement of employment is expected to be between $88,000 and $108,000 per year. At Dren Bio, pay ranges are determined by role, level(s), and location. The range displayed in this job posting reflects the minimum and maximum new hire pay for candidates located across all United States job markets.Employment Practices:
Dren Bio is an equal opportunity employer. Employment decisions are based on merit and business needs. Dren Bio will not discriminate against any job applicant because of race, color, national origin, ancestry, gender, sexual orientation, age, religion, creed, physical or mental disability, gender identity, medical condition, pregnancy, marital status, veteran status, or any other characteristic protected by federal, state or local law.Interested Applicants:
Please send resume and cover letter to careers@drenbio.com.
#J-18808-Ljbffr
About the Company:
Dren Bio (the "Company") is a privately held, clinical stage biopharmaceutical company focused on developing therapeutic antibodies for the treatment of cancer, autoimmune and other serious diseases. The Company's management team and scientific advisors have profound expertise covering the discovery and development of specially engineered antibodies. Dren Bio's pipeline encompasses a multitude of programs from its two distinct, wholly-owned technologies. The Company's lead development candidate, DR-01, induces antibody-mediated killing of a specific cell type known to play a key role in various hematologic malignancies and autoimmune disorders.Function:
Level:
Senior Research AssociateLocation:
Foster City, CAReporting Manager:
Principal Scientist, Oncology ResearchAbout the Opportunity:
Dren Bio is seeking a highly talented and motivated Senior Research Associate to support our oncology efforts for the treatment of solid tumors. The ideal candidate should have work experience in an industrial setting and have a basic background of immunology and/or cell biology with strong technical experience. The candidate will work with a cross-functional team of scientists (immunologists, cell biologists, biochemists, and protein engineers) to advance research-stage programs into early clinical development. The candidate will perform in vitro and ex vivo studies to assess efficacy of our novel therapeutic agents and elucidate their impact on myeloid cell functions within the tumor microenvironment.Role and Responsibilities:
Perform in vitro/ex vivo experiments to determine efficacy and MOA of therapeutic antibodies.Work collaboratively with other researchers to advance various therapeutic antibodies in different cancer indications.Specific tasks include recombinant cell line engineering, cell surface receptor quantification by flow, primary and cancer cell culture, isolation of immune cells from human blood, animal or human tissue processing, multi-color flow cytometry for immuno-phenotyping, cytokine profiling by MSD or Luminex, ADCC or ADCP assays using Incucyte and flow cytometry, DNA/RNA extraction for gene expression studies, various cellular assays (IP, western blot, and IF).Meticulous record-keeping of scientific data, methods, and study designs.Education, Experience and Qualification Requirements:
BA/BS or MS in a biology-related discipline with approximately 4+ years of experience in biopharmaceutical industry, or a combination of 4+ years of industrial and academic experience.Core Competencies, Knowledge and Skill Requirements:
Extensive experience in culturing variety of cancer cell lines including lymphoid & myeloid derived cell lines and primary cells.Experience with flow cytometry-based methods for characterizing cell surface expression.Well-versed in various data processing and analysis software (e.g. FlowJo, Prism, ImageJ).Detail-oriented, highly organized, and able to multi-task with multiple assignments.Strong written and verbal communication skills.Ability to work in a fast-paced environment and the flexibility to align daily work with project needs.Ability to set goals and prioritize tasks and resources to achieve superior work quality and efficiency.Salaries, Benefits and Other Employee Perks:
Dren Bio strongly believes in investing in, and rewarding, its employees. This philosophy is embodied in the Company’s total rewards program, which includes competitive cash compensation, equity incentive awards, and employer sponsored benefit offerings. The base pay range for this position at commencement of employment is expected to be between $88,000 and $108,000 per year. At Dren Bio, pay ranges are determined by role, level(s), and location. The range displayed in this job posting reflects the minimum and maximum new hire pay for candidates located across all United States job markets.Employment Practices:
Dren Bio is an equal opportunity employer. Employment decisions are based on merit and business needs. Dren Bio will not discriminate against any job applicant because of race, color, national origin, ancestry, gender, sexual orientation, age, religion, creed, physical or mental disability, gender identity, medical condition, pregnancy, marital status, veteran status, or any other characteristic protected by federal, state or local law.Interested Applicants:
Please send resume and cover letter to careers@drenbio.com.
#J-18808-Ljbffr