University of California
Multiple NIH-funded postdoctoral positions are available to study the molecular
University of California, San Francisco, California, United States, 94199
Home > Multiple NIH-funded postdoctoral positions are available to study the molecular mechanisms directing lung development, injury and repair in the laboratory of Cristina Alvira, MD, Benioff Endowed Professor of Pediatrics, Division of Critical Care Medicine.Multiple NIH-funded postdoctoral positions
Location: United StatesJob Posted Date: October 2, 2024Postdoc Positions at UCSFPopulation:Our current work employs single cell RNA and ATAC sequencing to profile the immune, mesenchymal, and endothelial landscape of the mouse lung during late embryonic and early postnatal development, focusing on identifying how lung cell diversity changes after birth and how distinct cellular subpopulations respond to injury and direct repair. The Alvira lab currently has three NIH-funded open postdoctoral positions to lead the following projects:Delineation of molecular mechanisms specializing lung capillary subtypes after birth, focusing on a putative capillary progenitor population unique to the developing lung (HL154002).Elucidating how lung immune cell diversity and phenotype is altered by early injury to the developing lung, and whether these alterations impair the immune response to subsequent inflammatory or infectious challenges (HL155828).The role of specific pathways in regulating lung pericyte function during postnatal development to direct both capillary growth and quiescence (HL160018).Techniques employed in the lab include in situ hybridization, confocal imaging, immunofluorescence, single-cell and single-nuclei RNA sequencing, bulk and single nuclei-ATAC sequencing, genetically modified mouse models of human disease, and gain and loss of function in primary cells.The Alvira Lab is highly collaborative. In addition to leading their own project, postdoctoral fellows have the opportunity to contribute to all ongoing projects in the lab. The Alvira lab also has numerous ongoing collaborations with investigators at Vanderbilt University, Columbia University, University of Colorado, Stanford University, and the University of New South Wales, providing our postdoctoral fellows additional exposure to leading investigators in lung developmental biology.In the Alvira Lab, we value diversity of background, perspective, and experience. We are committed to creating a highly collaborative, dynamic, and positive environment that fosters intellectual curiosity, creativity, and passion for the discovery of new knowledge. The Alvira lab is committed to ensuring an inclusive, safe environment where all lab members feel equally valued.Job Requirements:We are seeking highly motivated and driven candidates with a PhD, or MD/PhD and experience in molecular biology, cell biology, vascular biology, developmental biology, immunology, or a related field. Expertise in primary cell isolation and culture, flow cytometry, confocal imaging, and mouse models of disease is desired. The ideal candidate will demonstrate enthusiasm, passion for research, intellectual creativity, self-directed learning, and a history of working well in teams. Excellent organizational and communication skills and evidence of successful scientific writing are required.UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.How to Apply:Interested applicants should send: 1) a letter of interest summarizing their past research experience and career goals; 2) current CV; and 3) contact information for three references to
cristina.alvira@ucsf.edu .Location: Greater Bay Area, Peninsula, CaliforniaUCSF - University of CA San Francisco
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Location: United StatesJob Posted Date: October 2, 2024Postdoc Positions at UCSFPopulation:Our current work employs single cell RNA and ATAC sequencing to profile the immune, mesenchymal, and endothelial landscape of the mouse lung during late embryonic and early postnatal development, focusing on identifying how lung cell diversity changes after birth and how distinct cellular subpopulations respond to injury and direct repair. The Alvira lab currently has three NIH-funded open postdoctoral positions to lead the following projects:Delineation of molecular mechanisms specializing lung capillary subtypes after birth, focusing on a putative capillary progenitor population unique to the developing lung (HL154002).Elucidating how lung immune cell diversity and phenotype is altered by early injury to the developing lung, and whether these alterations impair the immune response to subsequent inflammatory or infectious challenges (HL155828).The role of specific pathways in regulating lung pericyte function during postnatal development to direct both capillary growth and quiescence (HL160018).Techniques employed in the lab include in situ hybridization, confocal imaging, immunofluorescence, single-cell and single-nuclei RNA sequencing, bulk and single nuclei-ATAC sequencing, genetically modified mouse models of human disease, and gain and loss of function in primary cells.The Alvira Lab is highly collaborative. In addition to leading their own project, postdoctoral fellows have the opportunity to contribute to all ongoing projects in the lab. The Alvira lab also has numerous ongoing collaborations with investigators at Vanderbilt University, Columbia University, University of Colorado, Stanford University, and the University of New South Wales, providing our postdoctoral fellows additional exposure to leading investigators in lung developmental biology.In the Alvira Lab, we value diversity of background, perspective, and experience. We are committed to creating a highly collaborative, dynamic, and positive environment that fosters intellectual curiosity, creativity, and passion for the discovery of new knowledge. The Alvira lab is committed to ensuring an inclusive, safe environment where all lab members feel equally valued.Job Requirements:We are seeking highly motivated and driven candidates with a PhD, or MD/PhD and experience in molecular biology, cell biology, vascular biology, developmental biology, immunology, or a related field. Expertise in primary cell isolation and culture, flow cytometry, confocal imaging, and mouse models of disease is desired. The ideal candidate will demonstrate enthusiasm, passion for research, intellectual creativity, self-directed learning, and a history of working well in teams. Excellent organizational and communication skills and evidence of successful scientific writing are required.UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.How to Apply:Interested applicants should send: 1) a letter of interest summarizing their past research experience and career goals; 2) current CV; and 3) contact information for three references to
cristina.alvira@ucsf.edu .Location: Greater Bay Area, Peninsula, CaliforniaUCSF - University of CA San Francisco
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