Vertex Pharmaceuticals
Senior Research Associate (Contract)
Vertex Pharmaceuticals, Boston, Massachusetts, us, 02298
Job Description:
Justification: to meet the increasing testing demand for VX-880/ VX-264 as well as provide support for visual inspection testing and investigation of VX-880 drug product.
Key Duties and Responsibilities:
Involved in the development, implementation and execution of release and characterization assays for identity, purity, impurity, and potency for cell therapy product.
Perform sample testing to support analytical and process development using a variety of techniques (e.g. ELISA, MSD, visual inspection, cell count and viability, flow cytometry, cell-based potency, SDS-PAGE, HPLC, and residual impurity characterization).
Manage sample inventory and lab equipment.
Troubleshoot, optimize, and trend assay performance.
Maintain excellent documentation of completed experiments (e.g. electronic lab notebook and study reports).
Be a strong team player contributing to group priorities and deliverables.
Perform other duties as assigned.
Knowledge and Skills:
Prior experience with several of the following techniques: ELISA, MSD, SDS-PAGE, Western blot, flow cytometry, RT-qPCR, ddPCR, HPLC, cell counting methods, and cell-based functional assays.
Intermediate statistical knowledge for analytical data analysis.
Ability to use literature to design proof of concept studies.
Experience in writing technical documents including development technical reports, qualification protocols, and qualification reports.
Excellent communication skills with the proven ability to build open and collaborative relationships and to work effectively as a member of a multidisciplinary team.
Experience with sample management and ELN/LIMS systems is preferred.
Education and Experience:
Master’s degree, Bachelor’s degree or equivalent experience in Cell Biology, Molecular Biology, Immunology, Biochemistry, Genetics or related field.
1-3 years of relevant industry experience.
Prior experience in cell therapy assay development is preferred.
Pay Range:
$39 - $43/HR
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Justification: to meet the increasing testing demand for VX-880/ VX-264 as well as provide support for visual inspection testing and investigation of VX-880 drug product.
Key Duties and Responsibilities:
Involved in the development, implementation and execution of release and characterization assays for identity, purity, impurity, and potency for cell therapy product.
Perform sample testing to support analytical and process development using a variety of techniques (e.g. ELISA, MSD, visual inspection, cell count and viability, flow cytometry, cell-based potency, SDS-PAGE, HPLC, and residual impurity characterization).
Manage sample inventory and lab equipment.
Troubleshoot, optimize, and trend assay performance.
Maintain excellent documentation of completed experiments (e.g. electronic lab notebook and study reports).
Be a strong team player contributing to group priorities and deliverables.
Perform other duties as assigned.
Knowledge and Skills:
Prior experience with several of the following techniques: ELISA, MSD, SDS-PAGE, Western blot, flow cytometry, RT-qPCR, ddPCR, HPLC, cell counting methods, and cell-based functional assays.
Intermediate statistical knowledge for analytical data analysis.
Ability to use literature to design proof of concept studies.
Experience in writing technical documents including development technical reports, qualification protocols, and qualification reports.
Excellent communication skills with the proven ability to build open and collaborative relationships and to work effectively as a member of a multidisciplinary team.
Experience with sample management and ELN/LIMS systems is preferred.
Education and Experience:
Master’s degree, Bachelor’s degree or equivalent experience in Cell Biology, Molecular Biology, Immunology, Biochemistry, Genetics or related field.
1-3 years of relevant industry experience.
Prior experience in cell therapy assay development is preferred.
Pay Range:
$39 - $43/HR
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